Relaxant Effects of Sodium Nitroprusside and NONOates in Rabbit Basilar Artery

NONOates are a new class of NO donors that have proven useful for studying the effects of spontaneous and chemically predictable NO release in biologic systems. In order to assess their potential as vasodilatatory drugs in the cerebrovascular bed we have compared the relaxant effects of the classica...

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Veröffentlicht in:	Pharmacology 1998-08, Vol.57 (2), p.79-87
Hauptverfasser:	Salom, Juan B., Barberá, María D., Centeno, José M., Ortí, Marta, Torregrosa, Germán, Alborch, Enrique
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Animals Basilar Artery - drug effects Basilar Artery - physiology Cyclic GMP - biosynthesis Diethylamines - pharmacology Endothelium, Vascular - drug effects Endothelium, Vascular - physiology Histamine - pharmacology Male Methylene Blue - pharmacology Nitric Oxide - pharmacology Nitroprusside - pharmacology Original Paper Polyamines - pharmacology Rabbits Spermine - pharmacology Structure-Activity Relationship Uridine Triphosphate Vasoconstriction - drug effects Vasodilation - drug effects Vasodilator Agents - pharmacology
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