Microparticle resins as a potential nasal drug delivery system for insulin

The application of various resins for the nasal delivery of insulin was examined in rabbits. Intranasal administration of human insulin (28 U, 1 mg) mixed with fractionated sodium polystyrene sulfonate powder (an anionic resin with a particle size of 20–45 μm) caused a rapid increase of the plasma i...

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Veröffentlicht in:	Journal of controlled release 1998-03, Vol.52 (1), p.81-87
Hauptverfasser:	Takenaga, Mitsuko, Serizawa, Yuzuru, Azechi, Yasutaka, Ochiai, Akira, Kosaka, Yasuo, Igarashi, Rie, Mizushima, Yutaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intranasal Animals Biological and medical sciences Blood Glucose - analysis Drug delivery Drug Delivery Systems General pharmacology Hormones. Endocrine system Humans Insulin Insulin - administration & dosage Male Medical sciences Nasal administration Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Rabbit Rabbits Resins Resins, Plant - administration & dosage
Online-Zugang:	Volltext
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