Evidence against alterations in Lecithin:cholesterol acyltransferase (LCAT) activity in Familial combined hyperlipidemia

Elevated concentrations of plasma cholesterol and triglycerides are characteristic of familial combined hyperlipidemia (FCHL) which may also present with reduced high density lipoprotein (HDL) cholesterol concentrations. Lecithin:cholesterol acyltransferase (LCAT) plays a key role in reverse cholest...

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Veröffentlicht in:	Atherosclerosis 1998-06, Vol.138 (2), p.383-389
Hauptverfasser:	Ribalta, Josep, La Ville, Agnes E, Carles Vallvé, Joan, Girona, Josefa, Masana, Lluı́s
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult apo A-I gene Apolipoprotein A-I - blood Apolipoprotein A-I - genetics Biological and medical sciences Disorders of blood lipids. Hyperlipoproteinemia Familial combined hyperlipidemia Female Genotype-status interaction HDL Humans Hyperlipidemia, Familial Combined - blood Hyperlipidemia, Familial Combined - enzymology Hyperlipidemia, Familial Combined - genetics LCAT Lipoproteins, HDL - blood Lipoproteins, HDL - genetics Male Medical sciences Metabolic diseases Middle Aged Phosphatidylcholine-Sterol O-Acyltransferase - metabolism Polymorphism Polymorphism, Genetic
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