Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1 Mediates Phagocytosis of Aged/Apoptotic Cells in Endothelial Cells

Recognition of the exposure of phosphatidyl-serine (PS) on the outer surface of plasma membrane has been implicated in the phagocytosis of aged/apoptotic cells. Because oxidized low-density lipoprotein (OxLDL) has been reported to block the phagocytosis, here we examined whether lectin-like OxLDL re...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1998-08, Vol.95 (16), p.9535-9540
Hauptverfasser:	Oka, Kozo, Sawamura, Tatsuya, Kikuta, Ken-Ichiro, Itokawa, Shigekazu, Kume, Noriaki, Kita, Toru, Masaki, Tomoh
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals Apoptosis Biochemistry Biological Sciences Blood Coagulation Cattle Cell Line Cells Cells, Cultured Cellular biology CHO Cells Cricetinae Endothelial cells Endothelium, Vascular - cytology Endothelium, Vascular - immunology Endothelium, Vascular - metabolism Epithelial cells Erythrocyte Aging Erythrocytes Humans Lectins - physiology Ligands Liposomes Membrane Lipids - metabolism Oxidation Phagocytes Phagocytosis Phagocytosis - physiology Phospholipids - metabolism Receptors, LDL - physiology Receptors, Oxidized LDL Scavenger Receptors, Class E T lymphocytes
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