The impact of HLA on long-term outcome after thymectomy for myasthenia gravis

In a retrospective series of 86 patients with myasthenia gravis, the only factors predictive of improvement in muscular strength after transsternal thymectomy were preoperative severity of myasthenia (90% versus 54%, p=0.0014) and HLA-B8 (79% versus 50%, p=0.0060) in bivariable and multivariable ana...

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Veröffentlicht in:	Journal of neuroimmunology 1998-08, Vol.88 (1), p.177-181
Hauptverfasser:	Machens, A, Löliger, C, Pichlmeier, U, Emskötter, Th, Busch, C, Izbicki, J.R
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Haplotypes HLA HLA-B8 Antigen - analysis HLA-B8 Antigen - genetics HLA-B8 Antigen - physiology Humans MHC Myasthenia gravis Myasthenia Gravis - immunology Myasthenia Gravis - physiopathology Myasthenia Gravis - surgery Outcome Prognosis Regression Analysis Retrospective Studies Severity of Illness Index Thymectomy Treatment Outcome
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