A single dose of zafirlukast reduces LTD4-induced bronchoconstriction in patients on maintenance inhaled corticosteroid therapy

Previous studies demonstrated that leukotriene receptor antagonists (LTRAs) are effective in reducing asthma symptoms and the airway response to inhaled leukotriene D4 (LTD4) in asthmatic patients receiving inhaled beta2-agonists alone. To investigate the efficacy of a single 20-mg dose of the oral...

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Veröffentlicht in:	Annals of allergy, asthma, & immunology asthma, & immunology, 1998-07, Vol.81 (1), p.43-49
Hauptverfasser:	SMITH, L. J, HANBY, L. A, LAVINS, B. J, SIMONSON, S. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Adrenal Cortex Hormones - therapeutic use Adult Anti-Asthmatic Agents - therapeutic use Asthma - drug therapy Asthma - physiopathology Biological and medical sciences Bronchoconstriction - drug effects Cross-Over Studies Double-Blind Method Female Humans Leukotriene D4 - pharmacology Male Medical sciences Pharmacology. Drug treatments Respiratory system Tosyl Compounds - blood Tosyl Compounds - therapeutic use
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