Regulation of IFN-gamma-receptor expression in human monocytes by granulocyte-macrophage colony-stimulating factor

The regulation of human IFN-gamma receptor (IFN-gamma-R) expression by granulocyte-macrophage CSF (GM-CSF) was investigated. On monocytic cell lines (U937, HL60) and peripheral blood monocytes, IFN-gamma-binding capacity was down-regulated upon incubation with GM-CSF. Scatchard plot analyses reveale...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of immunology (1950) 1990-11, Vol.145 (9), p.2914-2919
Hauptverfasser:	Fischer, T, Wiegmann, K, Bottinger, H, Morens, K, Burmester, G, Pfizenmaier, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Biological and medical sciences Blotting, Northern Cell Line Cell Membrane - metabolism Down-Regulation Fundamental and applied biological sciences. Psychology Fundamental immunology Gene Expression Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology Humans Immunobiology Interferon-gamma - metabolism Miscellaneous Molecular Weight Monocytes - metabolism Precipitin Tests Receptors, Cell Surface - metabolism Receptors, Immunologic - metabolism Receptors, Interferon Receptors, Tumor Necrosis Factor Recombinant Proteins Regulatory factors and their cellular receptors Tumor Necrosis Factor-alpha - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!