Passive immunization reduces immunity that results from simultaneous active immunization against tick-borne encephalitis virus in a mouse model

Concomitant administration of an antigen and antibodies of the respective specificity has been shown to result in reduced levels of actively produced antibodies. This has also recently been observed in a clinical trial on simultaneous passive and active immunization against tick-borne encephalitis v...

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Veröffentlicht in:	Vaccine 1998-05, Vol.16 (9), p.955-959
Hauptverfasser:	Kreil, Thomas R., Burger, Ingrid, Attakpah, Eva, Olas, Katja, Eibl, Martha M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Viral - administration & dosage Antibodies, Viral - biosynthesis Antigens, Viral - administration & dosage Biological and medical sciences Disease Models, Animal Dose-Response Relationship, Immunologic Encephalitis Viruses, Tick-Borne - immunology Encephalitis, Tick-Borne - immunology Encephalitis, Tick-Borne - prevention & control Female flavivirus Fundamental and applied biological sciences. Psychology Humans Immunization, Passive - adverse effects Mice Mice, Inbred BALB C Microbiology passive-active immunization simultaneous immunization Vaccination Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies Vaccines, Inactivated - administration & dosage Viral Vaccines - administration & dosage Virology
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