Parallel Hybridization Analysis of Multiple Protein Kinase Genes: Identification of Gene Expression Patterns Characteristic of Human Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is one of the major causes of human cancer deaths worldwide. To identify alterations of the genetic program associated with human HCC, we designed a new protocol based on the high-density replica method to analyze protein kinase gene expression in normal liver, HCC, an...

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Veröffentlicht in:	Genomics (San Diego, Calif.) Calif.), 1998-06, Vol.50 (3), p.331-340
Hauptverfasser:	Tsou, Ann-Ping, Wu, Keh-Ming, Tsen, Ten-Yen, Chi, Chin-Wen, Chiu, Jen-Hwey, Lui, Wing-Yiu, Hu, Cheng-Po, Chang, Chungming, Chou, Chen-Kung, Tsai, Shih-Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blotting, Northern Blotting, Western cancer Carcinoma, Hepatocellular - enzymology Carcinoma, Hepatocellular - genetics Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes expression Fundamental and applied biological sciences. Psychology gene Gene Expression Regulation, Neoplastic Gene Library Humans hybridization In Situ Hybridization - methods kinase liver Liver - enzymology Liver Neoplasms - enzymology Liver Neoplasms - genetics MAP Kinase Kinase Kinase 1 Molecular and cellular biology Oncogene Proteins - genetics Oncogene Proteins - metabolism Polymerase Chain Reaction Protein-Serine-Threonine Kinases - genetics Protein-Tyrosine Kinases - genetics Proto-Oncogene Proteins Receptor Protein-Tyrosine Kinases - genetics Receptor Protein-Tyrosine Kinases - metabolism Receptors, Fibroblast Growth Factor - genetics Receptors, Fibroblast Growth Factor - metabolism Receptors, Platelet-Derived Growth Factor - genetics Sequence Analysis, DNA Transcription, Genetic Tumor Cells, Cultured
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