Enhancement of brain choline levels by nicotinamide: mechanism of action

Following the subcutaneous (s.c.) administration of nicotinamide (10 mmol/kg), the brain and CSF levels of nicotinamide were increased to millimolar concentrations, but the concentrations of N-methylnicotinamide (NMN) in the CSF, and of NMN and NAD + in brain tissue were not significantly altered. C...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience letters 1998-06, Vol.249 (2), p.111-114
Hauptverfasser:	Erb, Christina, Klein, Jochen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry and metabolism Biological and medical sciences Brain - drug effects Brain - metabolism Central nervous system Choline Choline - cerebrospinal fluid Choline - metabolism Fundamental and applied biological sciences. Psychology Hippocampus - metabolism In Vitro Techniques Injections, Subcutaneous Liver - metabolism Male N-methylnicotinamide NAD - metabolism Niacinamide - analogs & derivatives Niacinamide - cerebrospinal fluid Niacinamide - metabolism Niacinamide - pharmacology Nicotinamide Phospholipase A 2 Rats Rats, Wistar Time Factors Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!