The relationship between striatal dopamine receptor binding and cognitive performance in Huntington's disease

Seventeen individuals at risk for Huntington's disease and five symptomatic patients, who had previously undergone [11C]SCH23390 and [11C]raclopride PET to assess in vivo levels of striatal dopamine D1 and D2 receptor binding, had neuropsychological assessment on a series of tests known to be s...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 1998-07, Vol.121 (7), p.1343-1355
Hauptverfasser:	LAWRENCE, A. D, WEEKS, R. A, BROOKS, D. J, ANDREWS, T. C, WATKINS, L. H. A, HARDING, A. E, ROBBINS, T. W, SAHAKIAN, B. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age of Onset Attention - physiology Biological and medical sciences Cognition - physiology Corpus Striatum - metabolism Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Discrimination (Psychology) - physiology Heterozygote Humans Huntington Disease - genetics Huntington Disease - metabolism Huntington Disease - psychology Learning - physiology Medical sciences Memory - physiology Neurology Neuropsychological Tests Receptors, Dopamine - metabolism Verbal Learning - physiology Visual Perception - physiology
Online-Zugang:	Volltext
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