Long-term administration of mouse nerve growth factor to adult rats with partial lesions of the cholinergic septohippocampal pathway

Nerve growth factor (NGF), a neurotrophic factor acting on cholinergic neurons of the basal forebrain, has been proposed as a treatment for Alzheimer's disease. Experimental support for its pharmacological use is derived from short-term studies showing that intraventricular administration of NG...

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Veröffentlicht in:Experimental neurology 1990-10, Vol.110 (1), p.25-38
Hauptverfasser: Junard, Emmanuel O., Montero, Claudia N., Hefti, Franz
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Sprache:eng
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