Quantitative analysis of the glucocorticoid receptor-DNA interaction at the mouse mammary tumor virus glucocorticoid response element

Purified glucocorticoid receptor (GR) from rat liver was used for a quantitative analysis of the protein-DNA interaction at specific GR-binding segments within the 5‘-long terminal repeat of the mouse mammary tumor virus. A truncated receptor was generated and used to demonstrate formation of hetero...

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Veröffentlicht in:	The Journal of biological chemistry 1990-10, Vol.265 (28), p.17222-17229
Hauptverfasser:	Perlmann, T, Eriksson, P, Wrange, O
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Binding Sites Biological and medical sciences Cell Nucleus Cross-Linking Reagents Deoxyribonuclease I DNA, Viral - genetics DNA, Viral - isolation & purification DNA, Viral - metabolism Fundamental and applied biological sciences. Psychology Interactions. Associations Intermolecular phenomena Liver - metabolism Mammary Tumor Virus, Mouse - genetics Molecular biophysics Molecular Sequence Data Rats Receptors, Glucocorticoid - isolation & purification Receptors, Glucocorticoid - metabolism Repetitive Sequences, Nucleic Acid Restriction Mapping Succinimides Triamcinolone Acetonide - metabolism
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