The separation of ipratropium bromide and its related compounds

Ipratropium bromide, the active component in ipratropium bromide metered dose inhalers (MDI), is used as a bronchodilator for the maintenance and treatment of bronchospasms associated with chronic obstructive pulmonary disease (COPD). The separation of ipratropium bromide, tropic acid, N-isopropyl-n...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 1998-08, Vol.17 (4), p.841-849
Hauptverfasser:	Simms, Peter J, Towne, Robert W, Gross, Cynthia S, Miller, Randall E
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biological and medical sciences Bronchodilator Agents - isolation & purification Chromatography, High Pressure Liquid - methods General pharmacology HPLC Hydrogen-Ion Concentration Inhalation solution Ipratropium - isolation & purification Ipratropium bromide MDI Medical sciences Pharmacology. Drug treatments Reproducibility of Results Spectrophotometry, Ultraviolet Stability indicating assay
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