The delta F508 mutation in cystic fibrosis patients of southern Italy

The delta F508 mutation in cystic fibrosis patients of southern Italy

Fifty one independent cystic fibrosis (CF) families originating from a restricted area of Southern Italy (Campania) have been analyzed for KM19 and XV2c haplotypes and the delta F508 mutation: 54% of the total CF chromosomes show the delta F508 mutation. No significative correlations were obtained w...

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Veröffentlicht in:Human genetics 1990-09, Vol.85 (4), p.430-431
Hauptverfasser: Sebastio, G, Castiglione, O, Incerti, B, Salvatore, D, Santamaria, F
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Sprache:eng
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Cystic Fibrosis - epidemiology
Cystic Fibrosis - genetics
genes
Humans
Italy - epidemiology
Mutation
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container_end_page 431
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container_start_page 430
container_title Human genetics
container_volume 85
creator Sebastio, G
Castiglione, O
Incerti, B
Salvatore, D
Santamaria, F
description Fifty one independent cystic fibrosis (CF) families originating from a restricted area of Southern Italy (Campania) have been analyzed for KM19 and XV2c haplotypes and the delta F508 mutation: 54% of the total CF chromosomes show the delta F508 mutation. No significative correlations were obtained when clinical score, radiological score, Pseudomonas colonization, or clinical symptoms at presentation were matched with the presence or absence of the delta F508 mutation.
doi_str_mv 10.1007/BF02428299
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source MEDLINE; SpringerLink Journals - AutoHoldings
subjects Cystic Fibrosis - epidemiology
Cystic Fibrosis - genetics
genes
Humans
Italy - epidemiology
Mutation
title The delta F508 mutation in cystic fibrosis patients of southern Italy
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