Interleukin-1 regulates interleukin-6 secretion in human oral squamous cell carcinoma in vitro: Possible influence of p53 but not human papillomavirus E6/E7

We have previously shown that interleukin-1 (IL-1) and IL-6 are constitutively produced by human oral squamous cell carcinoma (SCC) and some derived cell lines but not by cultured normal oral keratinocytes. To elucidate possible cytokine regulatory pathways that may contribute to oral SCC growth and...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1998-07, Vol.58 (14), p.3142-3149
Hauptverfasser:	WOODS, K. V, ADLER-STORTHZ, K, CLAYMAN, G. L, FRANCIS, G. M, GRIMM, E. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carcinoma, Squamous Cell - metabolism DNA-Binding Proteins - metabolism Humans Interleukin-1 - metabolism Interleukin-6 - secretion Medical sciences Mouth Neoplasms - metabolism Neoplasm Proteins - metabolism Nuclear Proteins - metabolism Otorhinolaryngology (head neck, general aspects and miscellaneous) Otorhinolaryngology. Stomatology Papillomaviridae Transcriptional Activation Tumor Cells, Cultured Tumor Suppressor Protein p53 - metabolism Tumors Viral Proteins
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