Quantification of the Nucleocytoplasmic Distribution of Wild Type and Modified Proteins Using Confocal Microscopy: Interaction between 90-kDa Heat Shock Protein (Hsp90α) and Glucocorticosteroid Receptor (GR)

The investigation of molecular interactions in whole cells by immunofluorescence was developed recently, based on the targeting of the protein partners to different cellular compartments and analysis of the modifications in their subcellular distribution resulting from their interaction. This paper...

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Veröffentlicht in:	Experimental cell research 1998-07, Vol.242 (1), p.255-264
Hauptverfasser:	Leclerc, Philippe, Jibard, Nicole, Meng, Xia, Schweizer-Groyer, Ghislaine, Fortin, Dominique, Rajkowski, Krzysztof, Kang, Ki, Catelli, Maria-Grazia, Baulieu, Etienne-Emile, Cadepond, Françoise
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Nucleus - chemistry Chickens COS Cells Cytoplasm - chemistry HSP90 Heat-Shock Proteins - analysis HSP90 Heat-Shock Proteins - genetics Humans Microscopy, Confocal - methods Nuclear Localization Signals Receptors, Glucocorticoid - analysis Receptors, Glucocorticoid - genetics Sequence Deletion
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