Influence of calcitriol on prolactin and prostaglandin production by human decidua

Receptors for calcitriol are described in human decidua. They exhibit a dissociation constant of 35 ± 6 pM and they are at concentrations similar to those found in other tissues (0.45 ± 0.04 fmol/μg DNA). They are highly specific for calcitriol since neither of the other vitamin D 3 derivatives nor...

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Veröffentlicht in:	Molecular and cellular endocrinology 1990-07, Vol.71 (3), p.177-183
Hauptverfasser:	Delvin, E.E., Gagnon, L., Arabian, A., Gibb, W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding, Competitive Biological and medical sciences Calcitriol Calcitriol - metabolism Calcitriol - pharmacology Cells, Cultured Decidua Decidua - drug effects Decidua - metabolism Female Fundamental and applied biological sciences. Psychology Gene Expression Regulation - drug effects Hormone metabolism and regulation Humans Mammalian female genital system Pregnancy Prolactin Prolactin - biosynthesis Prolactin - metabolism Prostaglandin Prostaglandins - biosynthesis Prostaglandins - metabolism Receptors, Calcitriol Receptors, Steroid - metabolism Steroid Steroids - metabolism Vertebrates: reproduction
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