Reduction of all- trans-retinal limits regeneration of visual pigment in mice

Absorption of photons by pigments in photoreceptor cells results in photoisomerization of the chromophore, 11- cis-retinal, to all- trans-retinal and activation of opsin. Photolysed chromophore is converted back to the 11- cis-configuration via several enzymatic steps in photoreceptor and retinal pi...

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Veröffentlicht in:	Vision research (Oxford) 1998-05, Vol.38 (10), p.1325-1333
Hauptverfasser:	Saari, John C, Garwin, Gregory G, Van Hooser, J.Preston, Palczewski, Krzysztof
Format:	Artikel
Sprache:	eng
Schlagworte:	All- trans-retinol dehydrogenase Animals Arrestin Arrestin - analysis Biological and medical sciences Darkness Eye and associated structures. Visual pathways and centers. Vision Eye Proteins - analysis Female Fundamental and applied biological sciences. Psychology Kinetics Light Male Membrane Proteins - analysis Mice Retinal Pigments - analysis Retinal Pigments - physiology Retinoids Retinoids - analysis Rhodopsin Rhodopsin - analysis Rod Cell Outer Segment - chemistry Time Factors Vertebrates: nervous system and sense organs Visual cycle Vitamin A - analysis
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