Sustained neonatal hyperthyroidism in the rat affects myelination in the central nervous system

We have carried out a study of the effects of sustained neonatal hyperthyroidism on myelin and on the oligodendroglial cells, in an effort to obtain further insight into the molecular mechanisms underlying the action of thyroid hormones on the central nervous system (CNS). Expression of the mRNAs of...

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Veröffentlicht in:	Journal of neuroscience research 1998-07, Vol.53 (2), p.251-259
Hauptverfasser:	Marta, Cecilia B., Adamo, Ana M., Soto, Eduardo F., Pasquini, Juana M.
Format:	Artikel
Sprache:	eng
Schlagworte:	2',3'-Cyclic-Nucleotide Phosphodiesterases - metabolism Animals Animals, Newborn - physiology apoptosis Apoptosis - drug effects Blotting, Northern Blotting, Western Central Nervous System - growth & development Central Nervous System - pathology DNA Probes Electrophoresis, Polyacrylamide Gel Female Flow Cytometry Hyperthyroidism - pathology Immunohistochemistry Male myelin Myelin Basic Protein - metabolism myelin genes myelin proteins Myelin Sheath - physiology neonatal hyperthyroidism oligodendroglial cell Rats Rats, Wistar transferrin Triiodothyronine - blood
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