A Priori Estimation of Phylogenetic Information Conserved in Aligned Sequences
A new phenomenological approach to explorative data analysis, the estimation of spectra of supporting positions, allows the search for conserved tracks left by phylogeny in DNA sequences. Spectra of supporting positions can be generated without reference to a tree topology or a model of sequence evo...
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Veröffentlicht in: | Molecular phylogenetics and evolution 1998-06, Vol.9 (3), p.358-365 |
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container_title | Molecular phylogenetics and evolution |
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creator | Wägele, Johann-Wolfgang Rödding, Friederike |
description | A new phenomenological approach to explorative data analysis, the estimation of spectra of supporting positions, allows the search for conserved tracks left by phylogeny in DNA sequences. Spectra of supporting positions can be generated without reference to a tree topology or a model of sequence evolution and are therefore an ideal tool for a priori estimation of information content of data sets. Analysis of published 18S rDNA alignments shows that signal to noise relationship varies greatly in a way not detected by conventional tree-construction methods. |
doi_str_mv | 10.1006/mpev.1998.0501 |
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Analysis of published 18S rDNA alignments shows that signal to noise relationship varies greatly in a way not detected by conventional tree-construction methods.</description><subject>Animals</subject><subject>Base Sequence</subject><subject>Conserved Sequence</subject><subject>DNA, Ribosomal - chemistry</subject><subject>DNA, Ribosomal - genetics</subject><subject>Evolution, Molecular</subject><subject>Humans</subject><subject>Molecular Sequence Data</subject><subject>Phylogeny</subject><subject>RNA, Ribosomal, 18S - genetics</subject><subject>Sequence Alignment</subject><subject>Sequence Homology, Nucleic Acid</subject><issn>1055-7903</issn><issn>1095-9513</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kEFLAzEQhYMotVav3oQ9eds1aZrd5FhK1YJoQT2HTTKpke2mJttC_71ZunjzNAPvzRveh9AtwQXBuHzY7uBQECF4gRkmZ2hMsGC5YISe9ztjeSUwvURXMX5jTAgTbIRGoiwrwekYvc6zdXA-uGwZO7etO-fbzNts_XVs_AZa6JzOVq31YdAWvo0QDmAy12bzxm3atL7Dzx5aDfEaXdi6iXAzzAn6fFx-LJ7zl7en1WL-kmtKRZcDLrkwitgZUEWt1gozrYytVMWxUZoaXrFKU0WgLq3himuoZumUWjMtLaMTdH_K3QWfXsdObl3U0DR1C34fJU9Vp1NOk7E4GXXwMQawchdSzXCUBMseoOwByh6g7AGmg7shea-2YP7sA7Gk85MOqd7BQZBRu767cQF0J413_0X_AgzFgRA</recordid><startdate>199806</startdate><enddate>199806</enddate><creator>Wägele, Johann-Wolfgang</creator><creator>Rödding, Friederike</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199806</creationdate><title>A Priori Estimation of Phylogenetic Information Conserved in Aligned Sequences</title><author>Wägele, Johann-Wolfgang ; Rödding, Friederike</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c339t-e0689db1f4e3b3fccb05cbdf7b780dbc3d8757c3b1ea6fd8b8ce743393fd26f53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Animals</topic><topic>Base Sequence</topic><topic>Conserved Sequence</topic><topic>DNA, Ribosomal - chemistry</topic><topic>DNA, Ribosomal - genetics</topic><topic>Evolution, Molecular</topic><topic>Humans</topic><topic>Molecular Sequence Data</topic><topic>Phylogeny</topic><topic>RNA, Ribosomal, 18S - genetics</topic><topic>Sequence Alignment</topic><topic>Sequence Homology, Nucleic Acid</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wägele, Johann-Wolfgang</creatorcontrib><creatorcontrib>Rödding, Friederike</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Molecular phylogenetics and evolution</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wägele, Johann-Wolfgang</au><au>Rödding, Friederike</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Priori Estimation of Phylogenetic Information Conserved in Aligned Sequences</atitle><jtitle>Molecular phylogenetics and evolution</jtitle><addtitle>Mol Phylogenet Evol</addtitle><date>1998-06</date><risdate>1998</risdate><volume>9</volume><issue>3</issue><spage>358</spage><epage>365</epage><pages>358-365</pages><issn>1055-7903</issn><eissn>1095-9513</eissn><abstract>A new phenomenological approach to explorative data analysis, the estimation of spectra of supporting positions, allows the search for conserved tracks left by phylogeny in DNA sequences. 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source | MEDLINE; Elsevier ScienceDirect Journals |
subjects | Animals Base Sequence Conserved Sequence DNA, Ribosomal - chemistry DNA, Ribosomal - genetics Evolution, Molecular Humans Molecular Sequence Data Phylogeny RNA, Ribosomal, 18S - genetics Sequence Alignment Sequence Homology, Nucleic Acid |
title | A Priori Estimation of Phylogenetic Information Conserved in Aligned Sequences |
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