Midterm angiographic outcome of single-vessel intracoronary stent placement in diabetic versus nondiabetic patients: A matched comparative study

Background It remains controversial whether diabetes is associated with an increased risk of restenosis after intracoronary stenting. Methods and Results We selected 42 diabetic patients and an equal number of nondiabetic patients with follow-up angiographic restudy after single-vessel stenting, mat...

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Veröffentlicht in:The American heart journal 1998-07, Vol.136 (1), p.150-155
Hauptverfasser: Lau, Kean-Wah, Ding, Zee-Pin, Johan, Abdullah, Lim, Yean-Leng
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container_title The American heart journal
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creator Lau, Kean-Wah
Ding, Zee-Pin
Johan, Abdullah
Lim, Yean-Leng
description Background It remains controversial whether diabetes is associated with an increased risk of restenosis after intracoronary stenting. Methods and Results We selected 42 diabetic patients and an equal number of nondiabetic patients with follow-up angiographic restudy after single-vessel stenting, matched for 4 important stent-related and angiographic variables (stent design, reference vessel size and expanded stent diameter, coronary vessel treated, and poststent residual diameter stenosis). The 2 patient groups did not differ in their baseline lesion severity and acute luminal gain. At 5-month angiographic assessment, the observed in-stent restenosis rate was significantly higher in diabetic than nondiabetic patients (40.5% vs 16.7%, P = 0.0157). It was highest in diabetic patients who received small stents
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Methods and Results We selected 42 diabetic patients and an equal number of nondiabetic patients with follow-up angiographic restudy after single-vessel stenting, matched for 4 important stent-related and angiographic variables (stent design, reference vessel size and expanded stent diameter, coronary vessel treated, and poststent residual diameter stenosis). The 2 patient groups did not differ in their baseline lesion severity and acute luminal gain. At 5-month angiographic assessment, the observed in-stent restenosis rate was significantly higher in diabetic than nondiabetic patients (40.5% vs 16.7%, P = 0.0157). It was highest in diabetic patients who received small stents &lt;3.0 mm in diameter and intermediate in diabetic patients who received larger stent sizes (55% vs 27%, P = 0.0675). The frequency of restenosis in nondiabetic patients, however, was low; it was 18% and 15% in those who received small stents and larger stents, respectively ( P = 0.7823). Conclusions Our data suggest that diabetes predisposes to an increased risk of in-stent restenosis, particularly in small vessels. (Am Heart J 1998;136:150-5.)</description><identifier>ISSN: 0002-8703</identifier><identifier>EISSN: 1097-6744</identifier><identifier>DOI: 10.1016/S0002-8703(98)70195-4</identifier><identifier>PMID: 9665232</identifier><identifier>CODEN: AHJOA2</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Biological and medical sciences ; Coronary Angiography ; Diabetes Complications ; Diseases of the cardiovascular system ; Follow-Up Studies ; Humans ; Medical sciences ; Middle Aged ; Myocardial Ischemia - complications ; Myocardial Ischemia - diagnostic imaging ; Myocardial Ischemia - surgery ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. 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Methods and Results We selected 42 diabetic patients and an equal number of nondiabetic patients with follow-up angiographic restudy after single-vessel stenting, matched for 4 important stent-related and angiographic variables (stent design, reference vessel size and expanded stent diameter, coronary vessel treated, and poststent residual diameter stenosis). The 2 patient groups did not differ in their baseline lesion severity and acute luminal gain. At 5-month angiographic assessment, the observed in-stent restenosis rate was significantly higher in diabetic than nondiabetic patients (40.5% vs 16.7%, P = 0.0157). It was highest in diabetic patients who received small stents &lt;3.0 mm in diameter and intermediate in diabetic patients who received larger stent sizes (55% vs 27%, P = 0.0675). The frequency of restenosis in nondiabetic patients, however, was low; it was 18% and 15% in those who received small stents and larger stents, respectively ( P = 0.7823). Conclusions Our data suggest that diabetes predisposes to an increased risk of in-stent restenosis, particularly in small vessels. (Am Heart J 1998;136:150-5.)</description><subject>Biological and medical sciences</subject><subject>Coronary Angiography</subject><subject>Diabetes Complications</subject><subject>Diseases of the cardiovascular system</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Myocardial Ischemia - complications</subject><subject>Myocardial Ischemia - diagnostic imaging</subject><subject>Myocardial Ischemia - surgery</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>Recurrence</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Stents</subject><subject>Treatment Outcome</subject><issn>0002-8703</issn><issn>1097-6744</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkctu1DAUhi0EKkPhESp5gRAsQp3Y8YUNqqpykVqxANaW4xxPjRI72M5IfYs-Mp7OaLasfPm_8x_7PwhdtORjS1p--ZMQ0jVSEPpeyQ-CtKpv2DO0aYkSDReMPUebE_ISvcr5Tz3yTvIzdKY47zvabdDjnR8LpBmbsPVxm8xy7y2Oa7FxBhwdzj5sJ2h2kDNM2IeSjI0pBpMecC4QCl4mY2He73zAozcDlGqxg5TXjEMMp6vFFF-x_Alf4dkUew8jrm0Wk6qwg2q3jg-v0Qtnpgxvjus5-v3l5tf1t-b2x9fv11e3jaVSlWbgrGV0EKSjjFswvZTWuoH3lFMpnROUtZJS03GQIFRHpRNKGNIyMTjFBnqO3h18lxT_rpCLnn22ME0mQFyzljUsKbmoYH8AbYo5J3B6SX6u39ct0ftJ6KdJ6H3MWkn9NAnNat3FscE6zDCeqo7RV_3tUTfZmsklE6zPJ6yjVDHSV-zzAYMaxs5D0tnWFC2MPoEteoz-Pw_5B_uBqAg</recordid><startdate>19980701</startdate><enddate>19980701</enddate><creator>Lau, Kean-Wah</creator><creator>Ding, Zee-Pin</creator><creator>Johan, Abdullah</creator><creator>Lim, Yean-Leng</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19980701</creationdate><title>Midterm angiographic outcome of single-vessel intracoronary stent placement in diabetic versus nondiabetic patients: A matched comparative study</title><author>Lau, Kean-Wah ; Ding, Zee-Pin ; Johan, Abdullah ; Lim, Yean-Leng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-b64143b702346cea588ccfb6536388ff7341833a26e8e79238f797a0147bf94b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Biological and medical sciences</topic><topic>Coronary Angiography</topic><topic>Diabetes Complications</topic><topic>Diseases of the cardiovascular system</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Myocardial Ischemia - complications</topic><topic>Myocardial Ischemia - diagnostic imaging</topic><topic>Myocardial Ischemia - surgery</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Recurrence</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Stents</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lau, Kean-Wah</creatorcontrib><creatorcontrib>Ding, Zee-Pin</creatorcontrib><creatorcontrib>Johan, Abdullah</creatorcontrib><creatorcontrib>Lim, Yean-Leng</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lau, Kean-Wah</au><au>Ding, Zee-Pin</au><au>Johan, Abdullah</au><au>Lim, Yean-Leng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Midterm angiographic outcome of single-vessel intracoronary stent placement in diabetic versus nondiabetic patients: A matched comparative study</atitle><jtitle>The American heart journal</jtitle><addtitle>Am Heart J</addtitle><date>1998-07-01</date><risdate>1998</risdate><volume>136</volume><issue>1</issue><spage>150</spage><epage>155</epage><pages>150-155</pages><issn>0002-8703</issn><eissn>1097-6744</eissn><coden>AHJOA2</coden><abstract>Background It remains controversial whether diabetes is associated with an increased risk of restenosis after intracoronary stenting. Methods and Results We selected 42 diabetic patients and an equal number of nondiabetic patients with follow-up angiographic restudy after single-vessel stenting, matched for 4 important stent-related and angiographic variables (stent design, reference vessel size and expanded stent diameter, coronary vessel treated, and poststent residual diameter stenosis). The 2 patient groups did not differ in their baseline lesion severity and acute luminal gain. At 5-month angiographic assessment, the observed in-stent restenosis rate was significantly higher in diabetic than nondiabetic patients (40.5% vs 16.7%, P = 0.0157). It was highest in diabetic patients who received small stents &lt;3.0 mm in diameter and intermediate in diabetic patients who received larger stent sizes (55% vs 27%, P = 0.0675). The frequency of restenosis in nondiabetic patients, however, was low; it was 18% and 15% in those who received small stents and larger stents, respectively ( P = 0.7823). Conclusions Our data suggest that diabetes predisposes to an increased risk of in-stent restenosis, particularly in small vessels. (Am Heart J 1998;136:150-5.)</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>9665232</pmid><doi>10.1016/S0002-8703(98)70195-4</doi><tpages>6</tpages></addata></record>
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subjects Biological and medical sciences
Coronary Angiography
Diabetes Complications
Diseases of the cardiovascular system
Follow-Up Studies
Humans
Medical sciences
Middle Aged
Myocardial Ischemia - complications
Myocardial Ischemia - diagnostic imaging
Myocardial Ischemia - surgery
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Recurrence
Retrospective Studies
Risk Factors
Stents
Treatment Outcome
title Midterm angiographic outcome of single-vessel intracoronary stent placement in diabetic versus nondiabetic patients: A matched comparative study
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