Synthetic full-length and truncated RANTES inhibit HIV-1 infection of primary macrophages

To determine the effect of beta-chemokines on HIV-1 infection of primary macrophages, and to search for chemokine derivatives devoid of biological effects but efficient at protecting CD4+ T lymphocytes and macrophages against HIV-1. Use of chemically synthesized molecules devoid of biological contam...

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Veröffentlicht in:	AIDS (London) 1998-06, Vol.12 (9), p.977-984
Hauptverfasser:	YLISASTIGUI, L, VIZZAVONA, J, DRAKOPOULOU, E, PAINDAVOINE, P, CALVO, C.-F, PARMENTIER, M, GLUCKMAN, J. C, VITA, C, BENJOUAD, A
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Animals Anti-HIV Agents - metabolism Anti-HIV Agents - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences Cells, Cultured Chemokine CCL5 - chemical synthesis Chemokine CCL5 - metabolism Chemokine CCL5 - pharmacology Chemotaxis CHO Cells Cricetinae HIV-1 - physiology Humans Leukocytes, Mononuclear - physiology Leukocytes, Mononuclear - virology Macrophages - drug effects Macrophages - physiology Macrophages - virology Medical sciences Pharmacology. Drug treatments Receptors, CCR5 - genetics Receptors, CCR5 - metabolism
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