Isoflurane-induced dilation of porcine coronary arterioles is mediated by ATP-sensitive potassium channels

Isoflurane causes increases in coronary blood flow in vivo, which are mediated by the adenosine triphosphate (ATP)-sensitive potassium channels, but the role of the arterioles (resistance vessels) in these responses is controversial. Medium porcine coronary arterioles (internal diameter, 172 +/- 51...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 1998-07, Vol.89 (1), p.182-189
Hauptverfasser:	XIPING ZHOU, ABBOUD, W, MANABAT, N. C, SALEM, M. R, CRYSTAL, G. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthetics, Inhalation - pharmacology Anesthetics. Neuromuscular blocking agents Animals Biological and medical sciences Coronary Vessels - drug effects Coronary Vessels - physiology Isoflurane - pharmacology Medical sciences Neuropharmacology Pharmacology. Drug treatments Potassium Channels - physiology Signal Transduction - drug effects Signal Transduction - physiology Swine Vasodilation - drug effects
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