Validation of the Point-EXACCT method in non-small cell lung carcinomas

K-ras point mutations are often detected in part of the lung carcinomas. For the validation of a highly sensitive and rapid assay for known point mutations, Point-EXACCT (Biochim Biophys Acta 1998; 1379:42-52), we analyzed 89 non-small cell lung carcinomas and compared the results with two sequencin...

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 1998-07, Vol.44 (7), p.1404-1409
Hauptverfasser:	Somers, Veerle A. M. C, Leimbach, Darcy A, Theunissen, Paul H. M. H, Murtagh, James J., Jr, Holloway, Brian, Ambergen, Anton W, Thunnissen, Frederik B. J. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carcinoma, Non-Small-Cell Lung - genetics DNA Mutational Analysis - methods DNA, Neoplasm - genetics Female Genes, ras Humans Investigative techniques, diagnostic techniques (general aspects) Lung Neoplasms - genetics Male Medical sciences Nucleic Acid Amplification Techniques Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Point Mutation Reproducibility of Results Respiratory system Sensitivity and Specificity
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