Response of Biochemical Markers of Bone Turnover to Hormone Replacement Therapy: Impact of Biological Variability

Biochemical markers of bone turnover may be useful to monitor patients taking hormone replacement therapy (HRT). The aim of this study was to assess the utility of markers in monitoring HRT by comparing the response of a large panel of markers to HRT with their within subject variability. We measure...

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Veröffentlicht in:	Journal of bone and mineral research 1998-07, Vol.13 (7), p.1124-1133
Hauptverfasser:	Hannon, Rosemary, Blumsohn, Aubrey, Naylor, Kim, Eastell, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorptiometry, Photon Acid Phosphatase - blood Age Factors Alkaline Phosphatase - blood Amino Acids - urine Biological and medical sciences Biomarkers - blood Biomarkers - urine Bone Density - drug effects Bone Remodeling - drug effects Estradiol - administration & dosage Estradiol - therapeutic use Estrogen Replacement Therapy Female Fundamental and applied biological sciences. Psychology Humans Hydroxyproline - urine Isoenzymes - blood Lumbar Vertebrae - drug effects Middle Aged Osteoporosis, Postmenopausal - blood Osteoporosis, Postmenopausal - drug therapy Osteoporosis, Postmenopausal - urine Peptide Fragments - blood Procollagen - blood Skeleton and joints Tartrate-Resistant Acid Phosphatase Vertebrates: osteoarticular system, musculoskeletal system
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