Serotonin 5-HT4 Receptor Agonistic Activity of the Optical Isomers of (±)-4-Amino-N-[2-(1-azabicyclo[3.3.0]octan-5-yl)ethyl]-5-chloro-2, 3-dihydro-2-methylbenzo[b]furan-7-carboxamide

The enantiomers, (R)-(-)-1 and (S)-(+)-1, of (±)-4-amino-N-[2-(1-azabicyclo[3.3.0]octan-5-yl)ethyl]-5-chloro-2, 3-dihydro-2-methylbenzo[b]furan-7-carboxamide [(±)-1] were prepared from optically active benzyl 4-acetylamino-2, 3-dihydro-2-methylbenzo[b]furan-7-carboxylate[(R)-(+)-6, (S)-(-)-6], respe...

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