Lack of association between outcome measures of nerve regeneration
Studies of nerve regeneration in rodents utilize at least one of three classes of outcome measures: electrophysiology, morphometry, and functional tests. The assumption that these measures are correlated was tested utilizing a data set of 16 variables. Significant correlations (Spearman's rho,...
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Veröffentlicht in: | Muscle & nerve 1998-08, Vol.21 (8), p.1095-1097 |
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creator | Munro, Catherine A. Szalai, John P. Mackinnon, Susan E. Midha, Rajiv |
description | Studies of nerve regeneration in rodents utilize at least one of three classes of outcome measures: electrophysiology, morphometry, and functional tests. The assumption that these measures are correlated was tested utilizing a data set of 16 variables. Significant correlations (Spearman's rho, P ⩽ 0.05) were found within variable classes; however, none were found between classes. The three commonly utilized outcome measures do not measure the same phenomenon but rather discrete aspects of nerve regeneration. © 1998 John Wiley & Sons, Inc. Muscle Nerve 21:1095–1097, 1998. |
doi_str_mv | 10.1002/(SICI)1097-4598(199808)21:8<1095::AID-MUS20>3.0.CO;2-S |
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The assumption that these measures are correlated was tested utilizing a data set of 16 variables. Significant correlations (Spearman's rho, P ⩽ 0.05) were found within variable classes; however, none were found between classes. The three commonly utilized outcome measures do not measure the same phenomenon but rather discrete aspects of nerve regeneration. © 1998 John Wiley & Sons, Inc. Muscle Nerve 21:1095–1097, 1998.</description><identifier>ISSN: 0148-639X</identifier><identifier>EISSN: 1097-4598</identifier><identifier>DOI: 10.1002/(SICI)1097-4598(199808)21:8<1095::AID-MUS20>3.0.CO;2-S</identifier><identifier>PMID: 9655134</identifier><identifier>CODEN: MUNEDE</identifier><language>eng</language><publisher>New York: John Wiley & Sons, Inc</publisher><subject>Animals ; Biological and medical sciences ; correlation ; Development. Senescence. Regeneration. Transplantation ; Electrophysiology ; Fundamental and applied biological sciences. 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The assumption that these measures are correlated was tested utilizing a data set of 16 variables. Significant correlations (Spearman's rho, P ⩽ 0.05) were found within variable classes; however, none were found between classes. The three commonly utilized outcome measures do not measure the same phenomenon but rather discrete aspects of nerve regeneration. © 1998 John Wiley & Sons, Inc. Muscle Nerve 21:1095–1097, 1998.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>correlation</subject><subject>Development. Senescence. Regeneration. Transplantation</subject><subject>Electrophysiology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>morphometry</subject><subject>Motor Activity - physiology</subject><subject>nerve regeneration</subject><subject>Nerve Regeneration - physiology</subject><subject>Peripheral Nervous System Diseases - pathology</subject><subject>Peripheral Nervous System Diseases - physiopathology</subject><subject>Rats</subject><subject>Rats, Inbred Lew</subject><subject>Tibial Nerve - injuries</subject><subject>Tibial Nerve - pathology</subject><subject>Tibial Nerve - transplantation</subject><subject>Treatment Outcome</subject><subject>Vertebrates: nervous system and sense organs</subject><subject>Walking - physiology</subject><subject>walking-track</subject><issn>0148-639X</issn><issn>1097-4598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtv1DAUhS0EKkPhJyBlgVC7yOBH7NgDqlRSKIMGRmLoY3flOA4KzaPYSR__HqcZDQuQWFi2zj0-9-hD6IjgOcGYvjnYLLPlIcEqjROu5AFRSmJ5SMlCvgsqXyyOlyfxl7MNxUdsjufZ-i2NN4_QbPflMZphkshYMHX5FD3z_ifGmEiR7qE9JTgnLJmh9yttrqKujLT3nal0X3VtlNv-1to26obedI2NGqv94Kwffa11NzZy9ocNrwf7c_Sk1LW3L7b3Pjr7-OF79ilerU-X2fEqNkmoHguZGm7KUiiNKaGMaqWKknEtOWY8V5wXuVaYFLQIx6YM5yJhglhKEiqMYPvo9ZR77bpfg_U9NJU3tq51a7vBQxoIcYVpMJ5PRuM6750t4dpVjXb3QDCMcAFGuDCSgpEUTHCBEpCjygECXHiACwwwZGugsAnBL7cNhryxxS52SzPMX23n2htdl063pvJ_tqciIUIG28Vku61qe_9Xuf91-1e1SQjJ8ZRc-d7e7ZK1uwKRspTDxddTuExTdXL-TcJn9htpW7A4</recordid><startdate>199808</startdate><enddate>199808</enddate><creator>Munro, Catherine A.</creator><creator>Szalai, John P.</creator><creator>Mackinnon, Susan E.</creator><creator>Midha, Rajiv</creator><general>John Wiley & Sons, Inc</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199808</creationdate><title>Lack of association between outcome measures of nerve regeneration</title><author>Munro, Catherine A. ; Szalai, John P. ; Mackinnon, Susan E. ; Midha, Rajiv</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4980-687c5cff69a021232a99df35a85035b955dba901d2d1d2e730b64361e21426c63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>correlation</topic><topic>Development. Senescence. Regeneration. Transplantation</topic><topic>Electrophysiology</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>morphometry</topic><topic>Motor Activity - physiology</topic><topic>nerve regeneration</topic><topic>Nerve Regeneration - physiology</topic><topic>Peripheral Nervous System Diseases - pathology</topic><topic>Peripheral Nervous System Diseases - physiopathology</topic><topic>Rats</topic><topic>Rats, Inbred Lew</topic><topic>Tibial Nerve - injuries</topic><topic>Tibial Nerve - pathology</topic><topic>Tibial Nerve - transplantation</topic><topic>Treatment Outcome</topic><topic>Vertebrates: nervous system and sense organs</topic><topic>Walking - physiology</topic><topic>walking-track</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Munro, Catherine A.</creatorcontrib><creatorcontrib>Szalai, John P.</creatorcontrib><creatorcontrib>Mackinnon, Susan E.</creatorcontrib><creatorcontrib>Midha, Rajiv</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Muscle & nerve</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Munro, Catherine A.</au><au>Szalai, John P.</au><au>Mackinnon, Susan E.</au><au>Midha, Rajiv</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lack of association between outcome measures of nerve regeneration</atitle><jtitle>Muscle & nerve</jtitle><addtitle>Muscle Nerve</addtitle><date>1998-08</date><risdate>1998</risdate><volume>21</volume><issue>8</issue><spage>1095</spage><epage>1097</epage><pages>1095-1097</pages><issn>0148-639X</issn><eissn>1097-4598</eissn><coden>MUNEDE</coden><abstract>Studies of nerve regeneration in rodents utilize at least one of three classes of outcome measures: electrophysiology, morphometry, and functional tests. The assumption that these measures are correlated was tested utilizing a data set of 16 variables. Significant correlations (Spearman's rho, P ⩽ 0.05) were found within variable classes; however, none were found between classes. The three commonly utilized outcome measures do not measure the same phenomenon but rather discrete aspects of nerve regeneration. © 1998 John Wiley & Sons, Inc. Muscle Nerve 21:1095–1097, 1998.</abstract><cop>New York</cop><pub>John Wiley & Sons, Inc</pub><pmid>9655134</pmid><doi>10.1002/(SICI)1097-4598(199808)21:8<1095::AID-MUS20>3.0.CO;2-S</doi><tpages>3</tpages></addata></record> |
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subjects | Animals Biological and medical sciences correlation Development. Senescence. Regeneration. Transplantation Electrophysiology Fundamental and applied biological sciences. Psychology morphometry Motor Activity - physiology nerve regeneration Nerve Regeneration - physiology Peripheral Nervous System Diseases - pathology Peripheral Nervous System Diseases - physiopathology Rats Rats, Inbred Lew Tibial Nerve - injuries Tibial Nerve - pathology Tibial Nerve - transplantation Treatment Outcome Vertebrates: nervous system and sense organs Walking - physiology walking-track |
title | Lack of association between outcome measures of nerve regeneration |
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