Histamine receptor subtypes mediating hyperpolarization in the isolated, perfused rat mesenteric pre-arteriolar bed

Histamine is a general dilator of rat blood vessels. We investigated the relative contribution of receptor subtypes to the rat mesenteric dilator responses initiated by histamine and related agonists. Histamine initiated dose, and endothelium-dependent, dilation of constricted mesenteric beds with a...

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Veröffentlicht in:	European journal of pharmacology 1998-04, Vol.347 (2), p.237-244
Hauptverfasser:	Adeagbo, Ayotunde S.O, Oriowo, Mabayoje A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arterioles - drug effects Arterioles - physiology Biological and medical sciences Dose-Response Relationship, Drug Electrophysiology Histamine - pharmacology Histamine Agonists - pharmacology Histamine and antagonists. Allergy Histamine Antagonists - pharmacology Histamine receptor subtype Male Medical sciences Perfused mesenteric bed Perfusion Pharmacology. Drug treatments Potassium - metabolism Potassium Channel Blockers Potassium Channels - metabolism Rats Rats, Sprague-Dawley Receptors, Histamine - physiology Splanchnic Circulation - drug effects Splanchnic Circulation - physiology Vascular hyperpolarization Vasodilation - drug effects Vasodilation - physiology
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