The C57BL/10Bg sps/sps mouse: A mutant with absence-like seizures; neurochemical and behavioral correlates

C57BL/10Bg sps/sps mice display behavioral arrest, similar to generalized absence seizures [7]. Compared with the parent strain C57BL/10Bg SPS/SPS, the activities of glutamate decarboxylase (GAD, E. C. 2.6.1.15), GABA aminotransferase (GABA-T, E. C. 2.6.1.19), aspartate aminotransferase (ASP-T, E. C...

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Veröffentlicht in:	Neuroscience letters 1990-07, Vol.114 (2), p.231-236
Hauptverfasser:	Ortiz, JoséG., Negrón, Arnaldo E., García, Mari T., Rosado, Julio E., Maldonaldo, Carmen S.
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Aminobutyrate Transaminase - metabolism Absence-like seizure Acoustic Stimulation Animals Aspartate Aminotransferases - metabolism Behavior Biological and medical sciences Brain - enzymology Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Epilepsy Fundamental and applied biological sciences. Psychology GABA Glutamate Glutamate Decarboxylase - metabolism Glutamate Dehydrogenase - metabolism Male Metabolism Mice Mice, Inbred C57BL - physiology Mice, Neurologic Mutants - physiology Motor Activity Open field Seizures - genetics Seizures - physiopathology Vertebrates: nervous system and sense organs
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