The development of bioengineered skin
Driven by the need for donor tissue for patients suffering from extensive burns, alternatives to autologous and cadaver-derived tissue have been under development for the past 20 years. Unilayered and bilayered models representing the skin's epidermal and/or dermal components have been develope...
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| Veröffentlicht in: | Trends in biotechnology (Regular ed.) 1998-06, Vol.16 (6), p.246-249 |
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| container_end_page | 249 |
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| container_issue | 6 |
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| container_title | Trends in biotechnology (Regular ed.) |
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| creator | Kirsner, Robert S Falanga, Vincent Eaglstein, William H |
| description | Driven by the need for donor tissue for patients suffering from extensive burns, alternatives to autologous and cadaver-derived tissue have been under development for the past 20 years. Unilayered and bilayered models representing the skin's epidermal and/or dermal components have been developed using both cells and matrix materials. In addition to their use in patients with extensive burns, trials using these products on refractory and challenging patients with both acute and chronic wounds have led to the commercial availability of some of these products. |
| doi_str_mv | 10.1016/S0167-7799(98)01196-2 |
| format | Article |
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Unilayered and bilayered models representing the skin's epidermal and/or dermal components have been developed using both cells and matrix materials. In addition to their use in patients with extensive burns, trials using these products on refractory and challenging patients with both acute and chronic wounds have led to the commercial availability of some of these products.</description><identifier>ISSN: 0167-7799</identifier><identifier>EISSN: 1879-3096</identifier><identifier>DOI: 10.1016/S0167-7799(98)01196-2</identifier><identifier>PMID: 9652135</identifier><identifier>CODEN: TRBIDM</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>bioengineered skin ; Biological and medical sciences ; Cell Transplantation ; Cells, Cultured ; chronic wounds ; Epidermis - cytology ; grafting ; Humans ; Medical sciences ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Skin Transplantation - methods ; Technology. Biomaterials. Equipments. Material. 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Unilayered and bilayered models representing the skin's epidermal and/or dermal components have been developed using both cells and matrix materials. In addition to their use in patients with extensive burns, trials using these products on refractory and challenging patients with both acute and chronic wounds have led to the commercial availability of some of these products.</description><subject>bioengineered skin</subject><subject>Biological and medical sciences</subject><subject>Cell Transplantation</subject><subject>Cells, Cultured</subject><subject>chronic wounds</subject><subject>Epidermis - cytology</subject><subject>grafting</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>Skin Transplantation - methods</subject><subject>Technology. Biomaterials. Equipments. 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Instrumentation</subject><subject>tissue therapy</subject><subject>wound therapy</subject><issn>0167-7799</issn><issn>1879-3096</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDtPwzAQgC0EKqXwEyplAARDwBc7djwhVPGSKjFQZstxLmDIo9hpJf49aRt1Zbkb7rvXR8gU6A1QELdvfZCxlEpdqeyaAigRJwdkDJlUMaNKHJLxHjkmJyF8UUqZVDAiIyXSBFg6JheLT4wKXGPVLmtsuqgto9y12Hy4BtFjEYVv15ySo9JUAc-GPCHvjw-L2XM8f316md3PY5tS3sUm5XnGElZwg5QLygpLjVSMGpMLaVIAoaySQhWJTIFmIARHCXlOk7K0JWcTcrmbu_TtzwpDp2sXLFaVabBdBd1_IhWX8C8IgitFRdaD6Q60vg3BY6mX3tXG_2qgeuNRbz3qjSStMr31qJO-bzosWOU1FvuuQVxfPx_qJlhTld401oU9lrAk5SB77G6HYW9t7dDrYB02Fgvn0Xa6aN0_h_wBdYyMmw</recordid><startdate>19980601</startdate><enddate>19980601</enddate><creator>Kirsner, Robert S</creator><creator>Falanga, Vincent</creator><creator>Eaglstein, William H</creator><general>Elsevier Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>19980601</creationdate><title>The development of bioengineered skin</title><author>Kirsner, Robert S ; Falanga, Vincent ; Eaglstein, William H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c504t-a54b8323d4ae04603dc0a7930aab67a51169c9769d2751081664e71bb02ffcf43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>bioengineered skin</topic><topic>Biological and medical sciences</topic><topic>Cell Transplantation</topic><topic>Cells, Cultured</topic><topic>chronic wounds</topic><topic>Epidermis - cytology</topic><topic>grafting</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Skin Transplantation - methods</topic><topic>Technology. Biomaterials. Equipments. Material. Instrumentation</topic><topic>tissue therapy</topic><topic>wound therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kirsner, Robert S</creatorcontrib><creatorcontrib>Falanga, Vincent</creatorcontrib><creatorcontrib>Eaglstein, William H</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Trends in biotechnology (Regular ed.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kirsner, Robert S</au><au>Falanga, Vincent</au><au>Eaglstein, William H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The development of bioengineered skin</atitle><jtitle>Trends in biotechnology (Regular ed.)</jtitle><addtitle>Trends Biotechnol</addtitle><date>1998-06-01</date><risdate>1998</risdate><volume>16</volume><issue>6</issue><spage>246</spage><epage>249</epage><pages>246-249</pages><issn>0167-7799</issn><eissn>1879-3096</eissn><coden>TRBIDM</coden><abstract>Driven by the need for donor tissue for patients suffering from extensive burns, alternatives to autologous and cadaver-derived tissue have been under development for the past 20 years. Unilayered and bilayered models representing the skin's epidermal and/or dermal components have been developed using both cells and matrix materials. In addition to their use in patients with extensive burns, trials using these products on refractory and challenging patients with both acute and chronic wounds have led to the commercial availability of some of these products.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>9652135</pmid><doi>10.1016/S0167-7799(98)01196-2</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0167-7799 |
| ispartof | Trends in biotechnology (Regular ed.), 1998-06, Vol.16 (6), p.246-249 |
| issn | 0167-7799 1879-3096 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79979471 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | bioengineered skin Biological and medical sciences Cell Transplantation Cells, Cultured chronic wounds Epidermis - cytology grafting Humans Medical sciences Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Skin Transplantation - methods Technology. Biomaterials. Equipments. Material. Instrumentation tissue therapy wound therapy |
| title | The development of bioengineered skin |
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