Thrombolytic Properties of Staphylokinase

We evaluated the properties of recombinant staphyloki-nase in comparison with those of tissue-type plasminogen activator (t-PA) and streptokinase (SK). The presence of fibrin(ogen) fragment FCB-2 in the reaction mixture increased plasminogen activation by staphylokinase more than 20-fold. Such chara...

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Veröffentlicht in:	Blood 1990-09, Vol.76 (5), p.925-929
Hauptverfasser:	Matsuo, Osamu, Okada, Kiyotaka, Fukao, Hideharu, Tomioka, Yoshiki, Ueshima, Shigeru, Watanuki, Masaaki, Sakai, Masashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Biological and medical sciences Cardiovascular system Fibrinogen - metabolism Fibrinolytic Agents Kinetics Medical sciences Metalloendopeptidases - isolation & purification Metalloendopeptidases - metabolism Miscellaneous Molecular Sequence Data Pharmacology. Drug treatments Recombinant Proteins - isolation & purification Recombinant Proteins - metabolism Streptokinase - metabolism Substrate Specificity Tissue Plasminogen Activator - metabolism
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