l-Arginine and NG-nitro- l-arginine methyl ester cause macromolecule extravasation in the microcirculation of awake hamsters

We investigated the effects of l-arginine and N G-nitro- l-arginine methyl ester ( l-NAME) on macromolecule extravasation in the microcirculation of awake hamsters by computer-assisted image analysis of the distribution of FITC (fluorescein isothiocyanate)-dextran fluorescence in dorsal fold skin pr...

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Veröffentlicht in:	European journal of pharmacology 1998-04, Vol.346 (2), p.275-282
Hauptverfasser:	Gimeno, Gilles, Carpentier, Patrick H, Desquand-Billiald, Stéphanie, Hanf, Rémy, Finet, Michel
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arginine - administration & dosage Arginine - pharmacology Biological and medical sciences Blood Pressure - drug effects Blood vessels and receptors Capillary Permeability - drug effects Cricetinae Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Enzyme Inhibitors - administration & dosage Enzyme Inhibitors - pharmacology Fundamental and applied biological sciences. Psychology Image Processing, Computer-Assisted In Vitro Techniques Inflammation Injections, Intravenous Male Mesocricetus Microcirculation Microcirculation - drug effects Microcirculation - metabolism Molecular and cellular biology Nitric oxide (NO) Nitric oxide (NO) synthase Nitric Oxide Synthase - antagonists & inhibitors Nitroarginine - administration & dosage Nitroarginine - pharmacology Permeability Regional Blood Flow - drug effects Skin - blood supply Skin - drug effects Skin - metabolism Spectrometry, Fluorescence Venules - anatomy & histology Vertebrates: cardiovascular system
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