Pharmacokinetics of Intravenous and Oral Losartan in Patients with Heart Failure

The pharmacokinetics of a selective AT1‐subtype, nonpeptide, orally active, angiotensin II receptor antagonist, losartan, were characterized in 11 patients with heart failure (New York Heart Association class II, n = 6; class III, n = 4; class IV, n = 1) after oral and intravenous administration. In...

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Veröffentlicht in:	Journal of clinical pharmacology 1998-06, Vol.38 (6), p.525-532
Hauptverfasser:	Lo, Man-Wai, Toh, Jenny, Emmert, Scott E., Ritter, Michael A., Furtek, Christine I., Lu, Hannah, Colucci, Wilson S., Uretsky, Barry F., MD, Ewa Rucinska
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Antihypertensive Agents - administration & dosage Antihypertensive Agents - blood Antihypertensive Agents - pharmacokinetics Biological and medical sciences Cardiovascular system Cross-Over Studies Female Half-Life Heart Failure - metabolism Humans Infusions, Intravenous Losartan - administration & dosage Losartan - blood Losartan - pharmacokinetics Male Medical sciences Middle Aged Miscellaneous Pharmacology. Drug treatments
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