Usefulness of Pulse-Wave Doppler Tissue Sampling and Dobutamine Stress Echocardiography for the Diagnosis of Right Coronary Artery Narrowing

To study the feasibility and diagnostic accuracy of right coronary artery (RCA) narrowing by right ventricular (RV) pulse-wave Doppler tissue sampling during dobutamine stress echocardiography (DSE), 30 patients (mean age 55 ± 9.5 years, 26 men) with suspected coronary artery disease underwent DSE (...

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Veröffentlicht in:The American journal of cardiology 1998-06, Vol.81 (12), p.1411-1415
Hauptverfasser: Rambaldi, Riccardo, Poldermans, Don, Fioretti, Paolo M, ten Cate, Folkert J, Vletter, Wim B, Bax, Jeroen J, Roelandt, Jos R.T.C
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container_end_page 1415
container_issue 12
container_start_page 1411
container_title The American journal of cardiology
container_volume 81
creator Rambaldi, Riccardo
Poldermans, Don
Fioretti, Paolo M
ten Cate, Folkert J
Vletter, Wim B
Bax, Jeroen J
Roelandt, Jos R.T.C
description To study the feasibility and diagnostic accuracy of right coronary artery (RCA) narrowing by right ventricular (RV) pulse-wave Doppler tissue sampling during dobutamine stress echocardiography (DSE), 30 patients (mean age 55 ± 9.5 years, 26 men) with suspected coronary artery disease underwent DSE (up to 40 μg/kg/min with additional atropine during submaximum heart rate responses). Pulse-wave Doppler tissue sampling of RV free walls close to the tricuspid annulus was performed in the apical 4-chamber view. The maximum velocity during the ejection phase, early, and late diastole was measured. Data from 5 consecutive beats were averaged. The measurements were repeated at rest, at low dose (10 μg/kg/min), and at peak dobutamine stress. The results were evaluated for the prediction of significant proximal or medium RCA narrowing (≥50% diameter stenosis, assessed by quantitative coronary angiography within the previous 3 months). A progressive increase of the ejection phase velocity (>25% between 10 μg/kg/min and peak stress) was predictive of a normal RCA, whereas a blunted increase and/or decrease (
doi_str_mv 10.1016/S0002-9149(98)00208-2
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Pulse-wave Doppler tissue sampling of RV free walls close to the tricuspid annulus was performed in the apical 4-chamber view. The maximum velocity during the ejection phase, early, and late diastole was measured. Data from 5 consecutive beats were averaged. The measurements were repeated at rest, at low dose (10 μg/kg/min), and at peak dobutamine stress. The results were evaluated for the prediction of significant proximal or medium RCA narrowing (≥50% diameter stenosis, assessed by quantitative coronary angiography within the previous 3 months). A progressive increase of the ejection phase velocity (&gt;25% between 10 μg/kg/min and peak stress) was predictive of a normal RCA, whereas a blunted increase and/or decrease (&lt;25% of increase) was predictive of significant RCA narrowing: sensitivity (95% confidence intervals): 82% (68 to 96), specificity: 78% (67 to 93), positive predictive value: 69% (52 to 86), negative predictive value: 88% (75 to 100), accuracy: 79% (65 to 94). Pulse-wave Doppler tissue sampling provided analyzable data in 100%, whereas the visual assessment of gray-scale images was possible only in 90%. 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subjects Cardiology
Cardiotonic Agents
Cardiovascular disease
Coronary Disease - diagnostic imaging
Coronary vessels
Dobutamine
Echocardiography, Doppler, Pulsed - methods
Electrocardiography
Female
Hemodynamics - drug effects
Humans
Male
Medical diagnosis
Middle Aged
Predictive Value of Tests
title Usefulness of Pulse-Wave Doppler Tissue Sampling and Dobutamine Stress Echocardiography for the Diagnosis of Right Coronary Artery Narrowing
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