Superior Hydrodynamics of a Modified Cavopulmonary Connection for the Norwood Operation

Background. In the Fontan circulation, energy consumption at the cavopulmonary connection is crucial. Our hypothesis was that a modification of the standard Norwood variant of cavopulmonary connection with an extended anastomosis would improve hydrodynamics. Methods. The in vitro hydrodynamics of tw...

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Veröffentlicht in:The Annals of thoracic surgery 1998-06, Vol.65 (6), p.1741-1745
Hauptverfasser: Sievers, Hans-Hinrich, Gerdes, Anja, Kunze, Jörg, Pfister, Gerd
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container_issue 6
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container_title The Annals of thoracic surgery
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creator Sievers, Hans-Hinrich
Gerdes, Anja
Kunze, Jörg
Pfister, Gerd
description Background. In the Fontan circulation, energy consumption at the cavopulmonary connection is crucial. Our hypothesis was that a modification of the standard Norwood variant of cavopulmonary connection with an extended anastomosis would improve hydrodynamics. Methods. The in vitro hydrodynamics of two different Perspex glass models resembling the Norwood variant of cavopulmonary connection (model I) and the modification (model II) were analyzed in a mock circulation at nonpulsatile flows of 2 to 5 L/min to simulate rest and exercise. The pulmonary flow split was varied to imitate varying lung resistances. Inferior-to-superior caval flow ratio and size of models were increased to simulate growth. Results. The pulmonary flow was preferentially directed to the left lung in model I and was better balanced in model II. Power losses increased exponentially with total flow in both models and were markedly higher in model I. These differences were attenuated in the larger models. Anastomotic turbulences were larger in model I. Power losses in both models were relatively insensitive to changes in pulmonary flow split. Conclusions. The proposed modification of the Norwood variant of cavopulmonary connection seems to be hydrodynamically advantageous and warrants further evaluation.
doi_str_mv 10.1016/S0003-4975(98)00252-5
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In the Fontan circulation, energy consumption at the cavopulmonary connection is crucial. Our hypothesis was that a modification of the standard Norwood variant of cavopulmonary connection with an extended anastomosis would improve hydrodynamics. Methods. The in vitro hydrodynamics of two different Perspex glass models resembling the Norwood variant of cavopulmonary connection (model I) and the modification (model II) were analyzed in a mock circulation at nonpulsatile flows of 2 to 5 L/min to simulate rest and exercise. The pulmonary flow split was varied to imitate varying lung resistances. Inferior-to-superior caval flow ratio and size of models were increased to simulate growth. Results. The pulmonary flow was preferentially directed to the left lung in model I and was better balanced in model II. Power losses increased exponentially with total flow in both models and were markedly higher in model I. These differences were attenuated in the larger models. Anastomotic turbulences were larger in model I. Power losses in both models were relatively insensitive to changes in pulmonary flow split. Conclusions. The proposed modification of the Norwood variant of cavopulmonary connection seems to be hydrodynamically advantageous and warrants further evaluation.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/S0003-4975(98)00252-5</identifier><identifier>PMID: 9647092</identifier><identifier>CODEN: ATHSAK</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Anastomosis, Surgical - methods ; Biological and medical sciences ; Energy Metabolism ; Fontan Procedure ; Hemorheology ; Humans ; Hypoplastic Left Heart Syndrome - physiopathology ; Hypoplastic Left Heart Syndrome - surgery ; Medical sciences ; Models, Anatomic ; Models, Cardiovascular ; Physical Exertion - physiology ; Polymethyl Methacrylate ; Pulmonary Artery - growth &amp; development ; Pulmonary Artery - surgery ; Pulmonary Circulation - physiology ; Regional Blood Flow - physiology ; Rest - physiology ; Surgery (general aspects). 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In the Fontan circulation, energy consumption at the cavopulmonary connection is crucial. Our hypothesis was that a modification of the standard Norwood variant of cavopulmonary connection with an extended anastomosis would improve hydrodynamics. Methods. The in vitro hydrodynamics of two different Perspex glass models resembling the Norwood variant of cavopulmonary connection (model I) and the modification (model II) were analyzed in a mock circulation at nonpulsatile flows of 2 to 5 L/min to simulate rest and exercise. The pulmonary flow split was varied to imitate varying lung resistances. Inferior-to-superior caval flow ratio and size of models were increased to simulate growth. Results. The pulmonary flow was preferentially directed to the left lung in model I and was better balanced in model II. Power losses increased exponentially with total flow in both models and were markedly higher in model I. These differences were attenuated in the larger models. Anastomotic turbulences were larger in model I. Power losses in both models were relatively insensitive to changes in pulmonary flow split. Conclusions. The proposed modification of the Norwood variant of cavopulmonary connection seems to be hydrodynamically advantageous and warrants further evaluation.</description><subject>Anastomosis, Surgical - methods</subject><subject>Biological and medical sciences</subject><subject>Energy Metabolism</subject><subject>Fontan Procedure</subject><subject>Hemorheology</subject><subject>Humans</subject><subject>Hypoplastic Left Heart Syndrome - physiopathology</subject><subject>Hypoplastic Left Heart Syndrome - surgery</subject><subject>Medical sciences</subject><subject>Models, Anatomic</subject><subject>Models, Cardiovascular</subject><subject>Physical Exertion - physiology</subject><subject>Polymethyl Methacrylate</subject><subject>Pulmonary Artery - growth &amp; development</subject><subject>Pulmonary Artery - surgery</subject><subject>Pulmonary Circulation - physiology</subject><subject>Regional Blood Flow - physiology</subject><subject>Rest - physiology</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. 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Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the heart</topic><topic>Vascular Resistance - physiology</topic><topic>Vena Cava, Inferior - physiology</topic><topic>Vena Cava, Superior - growth &amp; development</topic><topic>Vena Cava, Superior - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sievers, Hans-Hinrich</creatorcontrib><creatorcontrib>Gerdes, Anja</creatorcontrib><creatorcontrib>Kunze, Jörg</creatorcontrib><creatorcontrib>Pfister, Gerd</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sievers, Hans-Hinrich</au><au>Gerdes, Anja</au><au>Kunze, Jörg</au><au>Pfister, Gerd</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Superior Hydrodynamics of a Modified Cavopulmonary Connection for the Norwood Operation</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>1998-06-01</date><risdate>1998</risdate><volume>65</volume><issue>6</issue><spage>1741</spage><epage>1745</epage><pages>1741-1745</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><coden>ATHSAK</coden><abstract>Background. In the Fontan circulation, energy consumption at the cavopulmonary connection is crucial. Our hypothesis was that a modification of the standard Norwood variant of cavopulmonary connection with an extended anastomosis would improve hydrodynamics. Methods. The in vitro hydrodynamics of two different Perspex glass models resembling the Norwood variant of cavopulmonary connection (model I) and the modification (model II) were analyzed in a mock circulation at nonpulsatile flows of 2 to 5 L/min to simulate rest and exercise. The pulmonary flow split was varied to imitate varying lung resistances. Inferior-to-superior caval flow ratio and size of models were increased to simulate growth. Results. The pulmonary flow was preferentially directed to the left lung in model I and was better balanced in model II. Power losses increased exponentially with total flow in both models and were markedly higher in model I. These differences were attenuated in the larger models. 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subjects Anastomosis, Surgical - methods
Biological and medical sciences
Energy Metabolism
Fontan Procedure
Hemorheology
Humans
Hypoplastic Left Heart Syndrome - physiopathology
Hypoplastic Left Heart Syndrome - surgery
Medical sciences
Models, Anatomic
Models, Cardiovascular
Physical Exertion - physiology
Polymethyl Methacrylate
Pulmonary Artery - growth & development
Pulmonary Artery - surgery
Pulmonary Circulation - physiology
Regional Blood Flow - physiology
Rest - physiology
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the heart
Vascular Resistance - physiology
Vena Cava, Inferior - physiology
Vena Cava, Superior - growth & development
Vena Cava, Superior - surgery
title Superior Hydrodynamics of a Modified Cavopulmonary Connection for the Norwood Operation
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