Singlet Oxygen-Versus Nonsinglet Oxygen-Mediated Mechanisms of Sensitizer Photobleaching and Their Effects on Photodynamic Dosimetry

ABSTRACT We report the effects of singlet oxygen (1O2) and non‐1O2‐mediated sensitizer photobleaching on oxygen consumption and dosimetry during photodynamic therapy (PDT) of sensitized multicell tumor spheroids. We develop a theoretical model for the description of non‐1O2‐mediated photobleaching r...

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Veröffentlicht in:	Photochemistry and photobiology 1998-06, Vol.67 (6), p.612-625
Hauptverfasser:	Georgakoudi, Irene, Foster, Thomas H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Mice Models, Theoretical Oxygen - pharmacology Oxygen Consumption - drug effects Photochemistry Photochemotherapy Photosensitizing Agents - pharmacology Protoporphyrins - pharmacology Singlet Oxygen Tumor Cells, Cultured
Online-Zugang:	Volltext
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