Differential Regulation of Expression of Hyaluronan-Binding Proteoglycans in Developing Brain: Aggrecan, Versican, Neurocan, and Brevican

We have used a slot-blot radioimmunoassay to quantitate the levels of hyaluronan-binding chondroitin sulfate proteoglycans in developing rat brain from embryonic day 14 (E 14) to eight months postnatal. Recombinant nonhomologous regions of the core proteins were used for immunization to obtain polyc...

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Veröffentlicht in:	Biochemical and biophysical research communications 1998-06, Vol.247 (2), p.207-212
Hauptverfasser:	Milev, Peter, Maurel, Patrice, Chiba, Atsuro, Mevissen, Markus, Popp, Susanna, Yamaguchi, Yu, Margolis, Renée K., Margolis, Richard U.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aggrecans Alternative Splicing Animals Brain - embryology Brain - growth & development Brain - metabolism Brevican Carrier Proteins - chemistry Carrier Proteins - genetics Carrier Proteins - metabolism Chondroitin Sulfate Proteoglycans - chemistry Chondroitin Sulfate Proteoglycans - genetics Chondroitin Sulfate Proteoglycans - metabolism Extracellular Matrix Proteins Gene Expression Regulation, Developmental Hyaluronic Acid - metabolism Lectins, C-Type Nerve Tissue Proteins - chemistry Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Proteoglycans - chemistry Proteoglycans - genetics Proteoglycans - metabolism Rats RNA, Messenger - genetics RNA, Messenger - metabolism Versicans
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