Isoliquiritigenin: a new aldose reductase inhibitor from glycyrrhizae radix

Abstract Traditionally in Japan, some kampo medicines (traditional oriental herbal prescriptions) have long been used for the treatment of diabetic neuropathy. We have found that some aldose reductase inhibitors are included among these drugs. We further investigated the components of glycyrrhizae r...

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Veröffentlicht in:	Planta medica 1990-06, Vol.56 (3), p.254-258
Hauptverfasser:	Aida, K, Tawata, M, Shindo, H, Onaya, T, Sasaki, H, Yamaguchi, T, Chin, M, Mitsuhashi, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehyde Reductase - antagonists & inhibitors aldose reductase activity aldoses Animals Chalcone - analogs & derivatives Chalcone - isolation & purification Chalcone - pharmacology Chalcones diabetes Diabetes Mellitus, Experimental - drug therapy Diabetes Mellitus, Experimental - metabolism Drugs, Chinese Herbal - isolation & purification Drugs, Chinese Herbal - pharmacology Erythrocytes - drug effects Erythrocytes - metabolism Glycyrrhiza uralensis Humans inhibitors Male medicinal plants Molecular Structure plant extracts Plants, Medicinal - chemistry Propiophenones - isolation & purification Rats Rats, Inbred Strains sorbitol Sorbitol - metabolism Sugar Alcohol Dehydrogenases - antagonists & inhibitors
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