Harvesting hearts for long-term preservation. Detrimental effects of initial hypothermic infusion of cardioplegic solutions

Current procedure for harvesting human donor hearts for long-term storage before transplantation involves direct infusion of a hypothermic (4 degrees C) crystalloid cardioplegic solution into the normothermic (37 degrees C) heart in situ. We used the isolated perfused working rat heart preparation t...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 1990-09, Vol.100 (3), p.371-378
Hauptverfasser:	Takahashi, A, Hearse, DJ, Braimbridge, MV, Chambers, DJ
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Cardioplegic Solutions - pharmacology Clinical death. Palliative care. Organ gift and preservation Heart - drug effects Heart Transplantation - methods Hypothermia, Induced Ischemia Male Medical sciences Organ Preservation Rats Rats, Inbred Strains Reperfusion
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