Functional heterogeneity of Thy‐1 membrane microdomains in rat basophilic leukemia cells

Antibody‐mediated cross‐linking of Thy‐1 glycoprotein on the surface of rat mast cells and rat basophilic leukemia (RBL) cells initiates biochemical events which culminate in secretion of allergy mediators. Thy‐1, like some other glycosylphosphatidylinositol (GPI)‐anchored proteins, forms detergent‐...

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Veröffentlicht in:	European journal of immunology 1998-06, Vol.28 (6), p.1847-1858
Hauptverfasser:	Surviladze, Zurab, Dráberová, Lubica, Kubínová, Lucie, Dráber, Petr
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites Enzyme Activation Glycosylphosphatidylinositol‐anchored Lyn kinase Mast cell Mice Microscopy, Confocal Phosphatidylinositol Diacylglycerol-Lyase Phosphoinositide Phospholipase C Rat basophilic leukemia cell Rats src-Family Kinases - metabolism Thy-1 Antigens - immunology Thy‐1 Tumor Cells, Cultured Type C Phospholipases - pharmacology
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