Responsiveness of bone marrow erythropoietic stem cells (CFU‐E and BFU‐E) to recombinant human erythropoietin (rh‐Ep) in vitro in aplastic anemia and myelodysplastic syndrome

Responsiveness of bone marrow erythropoietic stem cells (CFU‐E and BFU‐E) to recombinant human erythropoietin (rh‐Ep) was examined in vitro in 23 patients with aplastic anemia and 14 with myelodysplastic syndrome (MDS) to investigate the clinical use of rh‐Ep for these diseases. Bone marrow mononucl...

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Veröffentlicht in:	American journal of hematology 1990-09, Vol.35 (1), p.6-12
Hauptverfasser:	Aoki, Isao, Homori, Masashi, Chikazawa, Hiroo, Ishikawa, Kyozo, Higashi, Katsumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia, Aplastic - pathology Anemia, Refractory - pathology Anemia, Refractory, with Excess of Blasts - pathology Anemia, Sideroblastic - pathology aplastic anemia Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Bone Marrow - pathology burst‐forming units–‐erythroid (BFU‐E) Cells, Cultured colony‐forming units–‐erythroid (CFU‐E) Dose-Response Relationship, Drug Erythroid Precursor Cells - drug effects Erythropoietin - pharmacology Humans Medical sciences myelodysplastic syndrome (MDS) Myelodysplastic Syndromes - pathology Pharmacology. Drug treatments recombinant human erythropoietin (rh‐Ep) Recombinant Proteins Reference Values
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