Pulmonary hypertension and reduced cardiac output during inhibition of nitric oxide synthesis in human septic shock

It has been suggested that inhibitors of nitric oxide synthesis are of value in the treatment of hypotension during sepsis. In this pilot study, we examined the effects of inhibition of nitric oxide synthesis by continuous infusion of N(omega)-nitro-L-arginine methyl ester (L-NAME) at 1.5 mg/kg/h in...

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Veröffentlicht in:	Shock (Augusta, Ga.) Ga.), 1998-06, Vol.9 (6), p.451-454
Hauptverfasser:	AVONTUUR, J. A. M, BIEWENGA, M, BUIJK, S. L. C. E, KANHAI, K. J. K, BRUINING, H. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Cardiac Output Emergency and intensive care: infection, septic shock Enzyme Inhibitors - therapeutic use Hemodynamics Humans Hypertension, Pulmonary - etiology Intensive care medicine Male Medical sciences NG-Nitroarginine Methyl Ester - therapeutic use Nitrates - blood Nitric Oxide - biosynthesis Nitric Oxide Synthase - antagonists & inhibitors Nitrites - blood Pilot Projects Shock, Septic - complications Shock, Septic - drug therapy Shock, Septic - physiopathology
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