Clozapine-responsive tremor in Parkinson's disease
Clozapine is an atypical neuroleptic medication that is free of parkinsonian side effects and that has been reported to ameliorate the tremor of Parkinson's disease. We report (with videotape illustration) the dramatic improvement of severe yet classic rest tremors in one elderly nonpsychotic p...
Gespeichert in:
| Veröffentlicht in: | Movement disorders 1990, Vol.5 (3), p.225-229 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 229 |
|---|---|
| container_issue | 3 |
| container_start_page | 225 |
| container_title | Movement disorders |
| container_volume | 5 |
| creator | Friedman, J. H. Lannon, M. C. |
| description | Clozapine is an atypical neuroleptic medication that is free of parkinsonian side effects and that has been reported to ameliorate the tremor of Parkinson's disease. We report (with videotape illustration) the dramatic improvement of severe yet classic rest tremors in one elderly nonpsychotic patient with Parkinson's disease and significant improvement in four others. We believe that clozapine, in low doses, may be a useful medication for the treatment of rest tremor in Parkinson's disease, even in cases without mental abnormalities. |
| doi_str_mv | 10.1002/mds.870050307 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_79957693</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>79957693</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4047-9cc3af51e8d3c66ae0c9288e1248e0d40fc3b31cfb9e95553b4d76953e7ce96f3</originalsourceid><addsrcrecordid>eNp9kDlPAzEQRi0EghAoKZHSANUGe71e2yWEW1ziEBKN5XhnJcNeeBIg_HoWZRWoqKaYN998eoRsMTpklMb7ZYZDJSkVlFO5RHpMcBapWMhl0qNKiYgzJdbIOuILpYwJlq6S1ZgrlXLVI_GoqL9s4yuIAmBTV-jfYTAJUNZh4KvBrQ2vvsK62sNB5hEswgZZyW2BsNnNPnk8OX4YnUWXN6fno4PLyCU0kZF2jttcMFAZd2lqgTodKwUsThTQLKG542POXD7WoIUQfJxkMtWCg3Sg05z3ye48twn12xRwYkqPDorCVlBP0UitRXvAWzCagy7UiAFy0wRf2jAzjJofR6Z1ZBaOWn67C56OS8gWdCel3e90e4vOFnmwlfP4G6oFFbwt3Cdyzn34Amb_PzVXR_d_G3SNPU7gc3HZujap5FKYp-tTI2P1HJ_dHZoL_g1Iso3I</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79957693</pqid></control><display><type>article</type><title>Clozapine-responsive tremor in Parkinson's disease</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Friedman, J. H. ; Lannon, M. C.</creator><creatorcontrib>Friedman, J. H. ; Lannon, M. C.</creatorcontrib><description>Clozapine is an atypical neuroleptic medication that is free of parkinsonian side effects and that has been reported to ameliorate the tremor of Parkinson's disease. We report (with videotape illustration) the dramatic improvement of severe yet classic rest tremors in one elderly nonpsychotic patient with Parkinson's disease and significant improvement in four others. We believe that clozapine, in low doses, may be a useful medication for the treatment of rest tremor in Parkinson's disease, even in cases without mental abnormalities.</description><identifier>ISSN: 0885-3185</identifier><identifier>EISSN: 1531-8257</identifier><identifier>DOI: 10.1002/mds.870050307</identifier><identifier>PMID: 2388638</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Aged ; Atypical neuroleptic ; Biological and medical sciences ; Clozapine ; Clozapine - therapeutic use ; Dibenzazepines - therapeutic use ; Dose-Response Relationship, Drug ; Female ; Humans ; Male ; Medical sciences ; Neuropharmacology ; Parkinson Disease - drug therapy ; Parkinson Disease - physiopathology ; Parkinson's disease ; Pharmacology. Drug treatments ; Psycholeptics: tranquillizer, neuroleptic ; Psychology. Psychoanalysis. Psychiatry ; Psychopharmacology ; Resting tremor ; Tremor</subject><ispartof>Movement disorders, 1990, Vol.5 (3), p.225-229</ispartof><rights>Copyright © 1990 Movement Disorder Society</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4047-9cc3af51e8d3c66ae0c9288e1248e0d40fc3b31cfb9e95553b4d76953e7ce96f3</citedby><cites>FETCH-LOGICAL-c4047-9cc3af51e8d3c66ae0c9288e1248e0d40fc3b31cfb9e95553b4d76953e7ce96f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fmds.870050307$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fmds.870050307$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,4010,27904,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19505355$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2388638$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Friedman, J. H.</creatorcontrib><creatorcontrib>Lannon, M. C.</creatorcontrib><title>Clozapine-responsive tremor in Parkinson's disease</title><title>Movement disorders</title><addtitle>Mov. Disord</addtitle><description>Clozapine is an atypical neuroleptic medication that is free of parkinsonian side effects and that has been reported to ameliorate the tremor of Parkinson's disease. We report (with videotape illustration) the dramatic improvement of severe yet classic rest tremors in one elderly nonpsychotic patient with Parkinson's disease and significant improvement in four others. We believe that clozapine, in low doses, may be a useful medication for the treatment of rest tremor in Parkinson's disease, even in cases without mental abnormalities.</description><subject>Aged</subject><subject>Atypical neuroleptic</subject><subject>Biological and medical sciences</subject><subject>Clozapine</subject><subject>Clozapine - therapeutic use</subject><subject>Dibenzazepines - therapeutic use</subject><subject>Dose-Response Relationship, Drug</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Neuropharmacology</subject><subject>Parkinson Disease - drug therapy</subject><subject>Parkinson Disease - physiopathology</subject><subject>Parkinson's disease</subject><subject>Pharmacology. Drug treatments</subject><subject>Psycholeptics: tranquillizer, neuroleptic</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopharmacology</subject><subject>Resting tremor</subject><subject>Tremor</subject><issn>0885-3185</issn><issn>1531-8257</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kDlPAzEQRi0EghAoKZHSANUGe71e2yWEW1ziEBKN5XhnJcNeeBIg_HoWZRWoqKaYN998eoRsMTpklMb7ZYZDJSkVlFO5RHpMcBapWMhl0qNKiYgzJdbIOuILpYwJlq6S1ZgrlXLVI_GoqL9s4yuIAmBTV-jfYTAJUNZh4KvBrQ2vvsK62sNB5hEswgZZyW2BsNnNPnk8OX4YnUWXN6fno4PLyCU0kZF2jttcMFAZd2lqgTodKwUsThTQLKG542POXD7WoIUQfJxkMtWCg3Sg05z3ye48twn12xRwYkqPDorCVlBP0UitRXvAWzCagy7UiAFy0wRf2jAzjJofR6Z1ZBaOWn67C56OS8gWdCel3e90e4vOFnmwlfP4G6oFFbwt3Cdyzn34Amb_PzVXR_d_G3SNPU7gc3HZujap5FKYp-tTI2P1HJ_dHZoL_g1Iso3I</recordid><startdate>1990</startdate><enddate>1990</enddate><creator>Friedman, J. H.</creator><creator>Lannon, M. C.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>8BM</scope></search><sort><creationdate>1990</creationdate><title>Clozapine-responsive tremor in Parkinson's disease</title><author>Friedman, J. H. ; Lannon, M. C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4047-9cc3af51e8d3c66ae0c9288e1248e0d40fc3b31cfb9e95553b4d76953e7ce96f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Aged</topic><topic>Atypical neuroleptic</topic><topic>Biological and medical sciences</topic><topic>Clozapine</topic><topic>Clozapine - therapeutic use</topic><topic>Dibenzazepines - therapeutic use</topic><topic>Dose-Response Relationship, Drug</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Neuropharmacology</topic><topic>Parkinson Disease - drug therapy</topic><topic>Parkinson Disease - physiopathology</topic><topic>Parkinson's disease</topic><topic>Pharmacology. Drug treatments</topic><topic>Psycholeptics: tranquillizer, neuroleptic</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopharmacology</topic><topic>Resting tremor</topic><topic>Tremor</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Friedman, J. H.</creatorcontrib><creatorcontrib>Lannon, M. C.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><jtitle>Movement disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Friedman, J. H.</au><au>Lannon, M. C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clozapine-responsive tremor in Parkinson's disease</atitle><jtitle>Movement disorders</jtitle><addtitle>Mov. Disord</addtitle><date>1990</date><risdate>1990</risdate><volume>5</volume><issue>3</issue><spage>225</spage><epage>229</epage><pages>225-229</pages><issn>0885-3185</issn><eissn>1531-8257</eissn><abstract>Clozapine is an atypical neuroleptic medication that is free of parkinsonian side effects and that has been reported to ameliorate the tremor of Parkinson's disease. We report (with videotape illustration) the dramatic improvement of severe yet classic rest tremors in one elderly nonpsychotic patient with Parkinson's disease and significant improvement in four others. We believe that clozapine, in low doses, may be a useful medication for the treatment of rest tremor in Parkinson's disease, even in cases without mental abnormalities.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>2388638</pmid><doi>10.1002/mds.870050307</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0885-3185 |
| ispartof | Movement disorders, 1990, Vol.5 (3), p.225-229 |
| issn | 0885-3185 1531-8257 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79957693 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Aged Atypical neuroleptic Biological and medical sciences Clozapine Clozapine - therapeutic use Dibenzazepines - therapeutic use Dose-Response Relationship, Drug Female Humans Male Medical sciences Neuropharmacology Parkinson Disease - drug therapy Parkinson Disease - physiopathology Parkinson's disease Pharmacology. Drug treatments Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Resting tremor Tremor |
| title | Clozapine-responsive tremor in Parkinson's disease |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T21%3A26%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clozapine-responsive%20tremor%20in%20Parkinson's%20disease&rft.jtitle=Movement%20disorders&rft.au=Friedman,%20J.%20H.&rft.date=1990&rft.volume=5&rft.issue=3&rft.spage=225&rft.epage=229&rft.pages=225-229&rft.issn=0885-3185&rft.eissn=1531-8257&rft_id=info:doi/10.1002/mds.870050307&rft_dat=%3Cproquest_cross%3E79957693%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79957693&rft_id=info:pmid/2388638&rfr_iscdi=true |