Post-trial NMDA receptor allosteric blockade differentially influences habituation of behavioral responses to novelty in the rat

The involvement of glutamatergic receptors of the N- methyl- d-aspartate (NMDA) type in long-term behavioral habituation (LTH) to a novel environment was investigated. To this aim, adult male Sprague-Dawley rats were first exposed to a Làt-maze. Horizontal (corner-crossings) and vertical activity (r...

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Veröffentlicht in:	Behavioural brain research 1990-07, Vol.39 (2), p.187-195
Hauptverfasser:	Carnevale, Ugo A.Gironi, Vitullo, Elisa, Sadile, Adolfo G.
Format:	Artikel
Sprache:	eng
Schlagworte:	[formula omitted] receptor Allosteric blockade Animals Arousal - drug effects Biological and medical sciences Brain - drug effects Discrimination Learning - drug effects Dose-Response Relationship, Drug Exploratory Behavior - drug effects Habituation, Psychophysiologic - drug effects Ketamine Ketamine - pharmacology Locomotor activity Long-term habituation Làt-maze Male Medical sciences Motor Activity - drug effects Orientation - drug effects Phencyclidine-like drug Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Rats Rats, Inbred Strains Rearing activity Receptors, N-Methyl-D-Aspartate Receptors, Neurotransmitter - drug effects Social Environment
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