Human Monocyte-derived Macrophages Secrete Two Forms of Proteoglycan-Macrophage Colony-stimulating Factor That Differ in Their Ability to Bind Low Density Lipoproteins

This study evaluated whether human monocyte-derived macrophages synthesize specific types of proteoglycans with lipoprotein-binding capability that could contribute to lipid retention in the arterial wall. After labeling with either [ 35 S]SO 4 or [ 35 S]methionine, macrophages secreted a high molec...

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Veröffentlicht in:	The Journal of biological chemistry 1998-06, Vol.273 (26), p.15985-15992
Hauptverfasser:	Chang, M Y, Olin, K L, Tsoi, C, Wight, T N, Chait, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Cells, Cultured Chondroitin ABC Lyase - metabolism Chromatography, Ion Exchange Heparitin Sulfate - metabolism Humans Lipoproteins, LDL - metabolism Macrophage Colony-Stimulating Factor - metabolism Macrophages - metabolism Molecular Weight Monocytes - metabolism Proteoglycans - metabolism
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