Mifepristone (RU 486) failure in an ovarian heterotopic pregnancy
A patient treated with mifepristone (RU 486), which successfully induced abortion of an intrauterine pregnancy, was discovered to have a heterotopic ovarian pregnancy resistant to this antiprogesterone. The ovarian pregnancy was removed with operative laparoscopy. This case demonstrates for the firs...
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Veröffentlicht in: | American journal of obstetrics and gynecology 1990-08, Vol.163 (2), p.543-544 |
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container_title | American journal of obstetrics and gynecology |
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creator | Levin, Jay H. Lacarra, Maria d'Ablaing, Gerrit Grimes, David A. Vermesh, Michael |
description | A patient treated with mifepristone (RU 486), which successfully induced abortion of an intrauterine pregnancy, was discovered to have a heterotopic ovarian pregnancy resistant to this antiprogesterone. The ovarian pregnancy was removed with operative laparoscopy. This case demonstrates for the first time that an ovarian pregnancy may be resistant to treatment with RU 486 at a dose adequate to abort an intrauterine pregnancy. |
doi_str_mv | 10.1016/0002-9378(90)91194-H |
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The ovarian pregnancy was removed with operative laparoscopy. This case demonstrates for the first time that an ovarian pregnancy may be resistant to treatment with RU 486 at a dose adequate to abort an intrauterine pregnancy.</description><identifier>ISSN: 0002-9378</identifier><identifier>EISSN: 1097-6868</identifier><identifier>DOI: 10.1016/0002-9378(90)91194-H</identifier><identifier>PMID: 2143627</identifier><identifier>CODEN: AJOGAH</identifier><language>eng</language><publisher>Philadelphia, PA: Mosby, Inc</publisher><subject>Abortion, Induced ; Adult ; antiprogesterone ; Biological and medical sciences ; Carboprost ; Diseases of mother, fetus and pregnancy ; Female ; Gynecology. Andrology. Obstetrics ; heterotopic ovarian pregnancy ; Humans ; Laparoscopy ; Medical sciences ; Mifepristone ; Mifepristone (RU 486) ; Ovary ; Pregnancy ; Pregnancy, Ectopic - therapy ; Pregnancy. Fetus. 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The ovarian pregnancy was removed with operative laparoscopy. This case demonstrates for the first time that an ovarian pregnancy may be resistant to treatment with RU 486 at a dose adequate to abort an intrauterine pregnancy.</description><subject>Abortion, Induced</subject><subject>Adult</subject><subject>antiprogesterone</subject><subject>Biological and medical sciences</subject><subject>Carboprost</subject><subject>Diseases of mother, fetus and pregnancy</subject><subject>Female</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>heterotopic ovarian pregnancy</subject><subject>Humans</subject><subject>Laparoscopy</subject><subject>Medical sciences</subject><subject>Mifepristone</subject><subject>Mifepristone (RU 486)</subject><subject>Ovary</subject><subject>Pregnancy</subject><subject>Pregnancy, Ectopic - therapy</subject><subject>Pregnancy. Fetus. Placenta</subject><issn>0002-9378</issn><issn>1097-6868</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEQhoMoWj_-gcJeFD2s5mM3HxehiFpBEUTPIZtMNLLdrcm20H9vaovePA3DPPMy8yB0TPAlwYRfYYxpqZiQ5wpfKEJUVU620IhgJUouudxGo19kD-2n9LlqqaK7aJeSinEqRmj8FDzMYkhD30Fx_vJWVJJfFN6Edh6hCF1huqJfmBhy_YABYj_0s2CLWYT3znR2eYh2vGkTHG3qAXq7u329mZSPz_cPN-PH0jIphtIb0zhbe8aIa6jkvmHMNkYpVwkqwRreyIaAE1LVRNAKVC0caxSj3HGPGTtAZ-vcWey_5pAGPQ3JQtuaDvp50kKpnERoBqs1aGOfUgSv839TE5eaYL0yp1ce9EqLVlj_mNOTvHayyZ83U3C_SxtVeX66mZtkTetjfj6kv2zFSE1rnrnrNQdZxiJA1MkG6Cy4EMEO2vXh_0O-AVaZiRw</recordid><startdate>19900801</startdate><enddate>19900801</enddate><creator>Levin, Jay H.</creator><creator>Lacarra, Maria</creator><creator>d'Ablaing, Gerrit</creator><creator>Grimes, David A.</creator><creator>Vermesh, Michael</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19900801</creationdate><title>Mifepristone (RU 486) failure in an ovarian heterotopic pregnancy</title><author>Levin, Jay H. ; Lacarra, Maria ; d'Ablaing, Gerrit ; Grimes, David A. ; Vermesh, Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-faabdc5f331db286fb33cba99d4728eca6b8b1ed78951724e957d3b9326d6f033</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Abortion, Induced</topic><topic>Adult</topic><topic>antiprogesterone</topic><topic>Biological and medical sciences</topic><topic>Carboprost</topic><topic>Diseases of mother, fetus and pregnancy</topic><topic>Female</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>heterotopic ovarian pregnancy</topic><topic>Humans</topic><topic>Laparoscopy</topic><topic>Medical sciences</topic><topic>Mifepristone</topic><topic>Mifepristone (RU 486)</topic><topic>Ovary</topic><topic>Pregnancy</topic><topic>Pregnancy, Ectopic - therapy</topic><topic>Pregnancy. Fetus. Placenta</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Levin, Jay H.</creatorcontrib><creatorcontrib>Lacarra, Maria</creatorcontrib><creatorcontrib>d'Ablaing, Gerrit</creatorcontrib><creatorcontrib>Grimes, David A.</creatorcontrib><creatorcontrib>Vermesh, Michael</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of obstetrics and gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Levin, Jay H.</au><au>Lacarra, Maria</au><au>d'Ablaing, Gerrit</au><au>Grimes, David A.</au><au>Vermesh, Michael</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mifepristone (RU 486) failure in an ovarian heterotopic pregnancy</atitle><jtitle>American journal of obstetrics and gynecology</jtitle><addtitle>Am J Obstet Gynecol</addtitle><date>1990-08-01</date><risdate>1990</risdate><volume>163</volume><issue>2</issue><spage>543</spage><epage>544</epage><pages>543-544</pages><issn>0002-9378</issn><eissn>1097-6868</eissn><coden>AJOGAH</coden><abstract>A patient treated with mifepristone (RU 486), which successfully induced abortion of an intrauterine pregnancy, was discovered to have a heterotopic ovarian pregnancy resistant to this antiprogesterone. The ovarian pregnancy was removed with operative laparoscopy. This case demonstrates for the first time that an ovarian pregnancy may be resistant to treatment with RU 486 at a dose adequate to abort an intrauterine pregnancy.</abstract><cop>Philadelphia, PA</cop><pub>Mosby, Inc</pub><pmid>2143627</pmid><doi>10.1016/0002-9378(90)91194-H</doi><tpages>2</tpages></addata></record> |
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language | eng |
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source | MEDLINE; Elsevier ScienceDirect Journals Complete |
subjects | Abortion, Induced Adult antiprogesterone Biological and medical sciences Carboprost Diseases of mother, fetus and pregnancy Female Gynecology. Andrology. Obstetrics heterotopic ovarian pregnancy Humans Laparoscopy Medical sciences Mifepristone Mifepristone (RU 486) Ovary Pregnancy Pregnancy, Ectopic - therapy Pregnancy. Fetus. Placenta |
title | Mifepristone (RU 486) failure in an ovarian heterotopic pregnancy |
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