Effective palliation for inoperable esophageal cancer using intensive intracavitary radiation
In a pilot study between May 1988 and May 1989, ten consecutive patients with advanced esophageal cancer were treated with a short intensive course of intraluminal curietherapy without external beam irradiation at the Kaiser Permanente‐Los Angeles Medical Center. Nine of ten patients achieved effect...
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Veröffentlicht in: | Journal of surgical oncology 1990-08, Vol.44 (4), p.234-237 |
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container_title | Journal of surgical oncology |
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creator | Fleischman, Erik H. Kagan, A. Robert Bellotti, John E. Streeter Jr, Oscar E. Harvey, James C. |
description | In a pilot study between May 1988 and May 1989, ten consecutive patients with advanced esophageal cancer were treated with a short intensive course of intraluminal curietherapy without external beam irradiation at the Kaiser Permanente‐Los Angeles Medical Center. Nine of ten patients achieved effective palliation comparable to that of standard external beam teletherapy from other series. Most patients had already failed other palliative modalities including chemotherapy, laser debridement, dilation, and electrocautery. The duration of response was generally longer than with these techniques. All patients completed therapy, and tolerance was excellent. Intraluminal irradiation is an attractive, effectual therapeutic alternative, especially in patients with advanced local or distant disease unlikely to tolerate 5 to 7 weeks of external beam therapy. |
doi_str_mv | 10.1002/jso.2930440409 |
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Robert ; Bellotti, John E. ; Streeter Jr, Oscar E. ; Harvey, James C.</creator><creatorcontrib>Fleischman, Erik H. ; Kagan, A. Robert ; Bellotti, John E. ; Streeter Jr, Oscar E. ; Harvey, James C.</creatorcontrib><description>In a pilot study between May 1988 and May 1989, ten consecutive patients with advanced esophageal cancer were treated with a short intensive course of intraluminal curietherapy without external beam irradiation at the Kaiser Permanente‐Los Angeles Medical Center. Nine of ten patients achieved effective palliation comparable to that of standard external beam teletherapy from other series. Most patients had already failed other palliative modalities including chemotherapy, laser debridement, dilation, and electrocautery. The duration of response was generally longer than with these techniques. All patients completed therapy, and tolerance was excellent. Intraluminal irradiation is an attractive, effectual therapeutic alternative, especially in patients with advanced local or distant disease unlikely to tolerate 5 to 7 weeks of external beam therapy.</description><identifier>ISSN: 0022-4790</identifier><identifier>EISSN: 1096-9098</identifier><identifier>DOI: 10.1002/jso.2930440409</identifier><identifier>PMID: 1696673</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Aged ; Body Weight ; Brachytherapy ; cesium ; endocurietherapy ; Esophageal Neoplasms - mortality ; Esophageal Neoplasms - radiotherapy ; Female ; Humans ; intraluminal treatment ; Male ; Palliative Care ; Survival Rate</subject><ispartof>Journal of surgical oncology, 1990-08, Vol.44 (4), p.234-237</ispartof><rights>Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4739-172e5a54c80213de0bd1082ccd949637fb22a8668e6b70f00b573cff941314993</citedby><cites>FETCH-LOGICAL-c4739-172e5a54c80213de0bd1082ccd949637fb22a8668e6b70f00b573cff941314993</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjso.2930440409$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjso.2930440409$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1696673$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fleischman, Erik H.</creatorcontrib><creatorcontrib>Kagan, A. Robert</creatorcontrib><creatorcontrib>Bellotti, John E.</creatorcontrib><creatorcontrib>Streeter Jr, Oscar E.</creatorcontrib><creatorcontrib>Harvey, James C.</creatorcontrib><title>Effective palliation for inoperable esophageal cancer using intensive intracavitary radiation</title><title>Journal of surgical oncology</title><addtitle>J. Surg. Oncol</addtitle><description>In a pilot study between May 1988 and May 1989, ten consecutive patients with advanced esophageal cancer were treated with a short intensive course of intraluminal curietherapy without external beam irradiation at the Kaiser Permanente‐Los Angeles Medical Center. Nine of ten patients achieved effective palliation comparable to that of standard external beam teletherapy from other series. Most patients had already failed other palliative modalities including chemotherapy, laser debridement, dilation, and electrocautery. The duration of response was generally longer than with these techniques. All patients completed therapy, and tolerance was excellent. Intraluminal irradiation is an attractive, effectual therapeutic alternative, especially in patients with advanced local or distant disease unlikely to tolerate 5 to 7 weeks of external beam therapy.</description><subject>Aged</subject><subject>Body Weight</subject><subject>Brachytherapy</subject><subject>cesium</subject><subject>endocurietherapy</subject><subject>Esophageal Neoplasms - mortality</subject><subject>Esophageal Neoplasms - radiotherapy</subject><subject>Female</subject><subject>Humans</subject><subject>intraluminal treatment</subject><subject>Male</subject><subject>Palliative Care</subject><subject>Survival Rate</subject><issn>0022-4790</issn><issn>1096-9098</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEFP3DAQRi3UCrbAlRtSTr1lO469duZYIdi2QnAoCKlSZTnOGEyzSWpnafn3GAUVceppRpr3PY0-xo44LDlA9ek-DcsKBUgJEnCHLTigKhGwfscWGahKqRH22IeU7gEAUcldtssVKqXFgv089Z7cFB6oGG3XBTuFoS_8EIvQDyNF23RUUBrGO3tLtiuc7R3FYptCf5uRifr0nM1btM4-hMnGxyLadhYdsPfedokOX-Y-uz47vTr5Up5frr-efD4vndQCS64rWtmVdDVUXLQETcuhrpxrUaIS2jdVZWulalKNBg_QrLRw3qPkgktEsc8-zt4xDr-3lCazCclR19mehm0yGjOKoDK4nEEXh5QieTPGsMk_Gw7muU-T-zSvfebA8Yt522yofcXnAvMd5_uf0NHjf2zm2_fLN-5yzoY00d9_WRt_mazWK3NzsTacr3_AOi834glzW5Ha</recordid><startdate>199008</startdate><enddate>199008</enddate><creator>Fleischman, Erik H.</creator><creator>Kagan, A. 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Robert</au><au>Bellotti, John E.</au><au>Streeter Jr, Oscar E.</au><au>Harvey, James C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effective palliation for inoperable esophageal cancer using intensive intracavitary radiation</atitle><jtitle>Journal of surgical oncology</jtitle><addtitle>J. Surg. Oncol</addtitle><date>1990-08</date><risdate>1990</risdate><volume>44</volume><issue>4</issue><spage>234</spage><epage>237</epage><pages>234-237</pages><issn>0022-4790</issn><eissn>1096-9098</eissn><abstract>In a pilot study between May 1988 and May 1989, ten consecutive patients with advanced esophageal cancer were treated with a short intensive course of intraluminal curietherapy without external beam irradiation at the Kaiser Permanente‐Los Angeles Medical Center. Nine of ten patients achieved effective palliation comparable to that of standard external beam teletherapy from other series. Most patients had already failed other palliative modalities including chemotherapy, laser debridement, dilation, and electrocautery. The duration of response was generally longer than with these techniques. All patients completed therapy, and tolerance was excellent. Intraluminal irradiation is an attractive, effectual therapeutic alternative, especially in patients with advanced local or distant disease unlikely to tolerate 5 to 7 weeks of external beam therapy.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>1696673</pmid><doi>10.1002/jso.2930440409</doi><tpages>4</tpages></addata></record> |
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source | MEDLINE; Wiley-Blackwell Full Collection |
subjects | Aged Body Weight Brachytherapy cesium endocurietherapy Esophageal Neoplasms - mortality Esophageal Neoplasms - radiotherapy Female Humans intraluminal treatment Male Palliative Care Survival Rate |
title | Effective palliation for inoperable esophageal cancer using intensive intracavitary radiation |
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