Comparison of Magnetic Resonance Imaging and Ultrasonography in Staging Early Prostate Cancer: Results of a Multi-Institutional Cooperative Trial

PROSTATE cancer is the most prevalent cancer in men, the most frequently diagnosed cancer, and the second most frequent cause of death due to cancer in American men. 1 2 3 The approach to treatment varies and is dependent on the extent of cancer at the time of diagnosis. Although new imaging techniques have been developed over the past 10 to 20 years to increase staging accuracy and thereby lead to better treatment decisions, the increasing need for cost containment has raised questions about the value of these approaches. Computed tomography was initially used to stage prostate cancer, 4 5 6 but since it cannot identify . . .