The Advanced Glycation Endproduct Pentosidine Induces the Expression of PDGF-B in Human Retinal Pigment Epithelial Cells

Advanced glycation endproducts have been implicated in a number of diabetic and aging changes. Some of these effects occur in part through induction of cytokines such as platelet-derived growth factor (PDGF), which is expressed by the retinal pigment epithelium (RPE). In this study, cultures of RPE...

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Veröffentlicht in:Experimental eye research 1998-04, Vol.66 (4), p.411-419
Hauptverfasser: HANDA, JAMES T., REISER, KAREN M., MATSUNAGA, HIROSHI, HJELMELAND, LEONARD M.
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Sprache:eng
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